社区肺癌高危人群低剂量螺旋C筛查结果分析.docVIP

社区肺癌高危人群低剂量螺旋CT筛查结果分析 　　摘 要 目的：探讨对社区40岁及以上肺癌高危人群进行低剂量螺旋CT（LDCT）的筛查效果。方法：从本社区肺癌高危人群数据库中登记的898例肺癌高危人群进行LDCT筛查。以发现至少1个≥4 mm非钙化结节为LDCT筛查阳性结果。结果：检出阳性结节者共137名（15.3%），其中男性结节阳性检出率14.6%，女性检出率15.7%，差别无统计学意义（P0.05）。各年龄段阳性结节检出率差异无统计学意义（P0.05）。共筛查出肺癌3例，肺癌检出率为0.33%，占结节阳性者的2.2%。其中有1例是早期肺癌，肺癌早期诊断率33.33%，3例肺癌年龄都在60岁以上。结论：LDCT在肺癌高危人群筛查应用，有助于提高肺癌的早期诊断率和非钙化结节的检出率，60岁以上高危人群的肺癌筛查应该引起高度关注。 中国论文网 /6/viewhtm　　关键词 肺癌；高危人群；筛查；低剂量螺旋CT 　　中图分类号：R734.2 文献标志码：A 文章编号：1006-1533（2018）02- 　　Analysis of the results of low-dose spiral CT screening for lung cancer in high-risk population in a community 　　WEI Xinping1， MA Xuedong1， JIANG Wei1， YANG Suhua2（1.General Department of Gumei Community Health Service Center of Minhang District， Shanghai 201102， China；2.Pr eventive-Care Division of Gumei Community Health Service Center of Minhang District， Shanghai 201102， China） 　　ABSTRACT Objective： To investigate the effect of low-dose spiral computed tomography CT （LDCT） screening in highrisk population aged over 40 years old in the community. Methods： LDCT screening was performed in 898 high-risk individuals with lung cancer registered from the database of high risk population of lung cancer in this community. LDCT result that revealed at least one ≥4mm non-calcified nodule was classified as the positive outcome. Results： A total of 137（15.3%） positive nodules were detected， among them the positive rate of male nodules was 14.6%， and that of the female was 15.7% and the difference was not statistically significant（P0.05）. Each age positive nodules detection rate had no significant difference（P0.05）. A total of 3 cases of lung cancer were detected by screening， and the detection rate of lung cancer was 0.33%， accounting for 2.2% of the cases with positive nodules. Among them， 1 cases were early lung cancer， the early diagnosis rate of lung cancer was 33.33%， and 3 cases of lung cancer were all over 60 years old. Conclusion： The application of LDCT in screening high-risk population of lung cancer is