精索静脉曲张性重度少精或无精患者手术治疗实验室评价.docVIP

精索静脉曲张性重度少精或无精患者手术治疗实验室评价 　　The laboratory evaluation on the effect of surgical treatment for varicocele―associated severe spermacrasia or azoospermia patients 　　[Abstract] Objectives： To evaluate the efficacy of high ligation of varicocele to varicocele-associated severe spermacrasia or azoospermia patients. Methods： 20 varicocele-associated severe spermacrasia （sperm density less than 2 million per ml ）or azoospermia patients（the former is 12 cases ， the latter is 8 cases， gas pains of scrotum is 5 cases）with high ligation of varicocele， sperm quality and gonadal hormones （FSH， LH， T， E2， PRL）of these cases were measured and contrasted before operation and 2， 4， 8 months after operation. 10 varicocele-associated severe spermacrasiaor azoospermia patients refused high ligation of varicocele as control group. Results： Compared with the before operation and 2， 4， 8 months after operation ， the sperm quality and gonadal hormones no significant difference（Pgt;0.05）， but the scrotum gas pains of the patients markedly release or disappear. Compared with the experimental group and control group， the sperm quality and gonadal hormones no significant difference（Pgt;0.05）. Conclusions： The high ligation of varicocele on varicocele-associated severe spermacrasia or azoospermia are inefficiency.It is not to recommend that these patients who want to improve their sperm quality to received the operation. 　　Key words： Varicocele ; High ligation of varicocele; Treatment; Sperm quality; Gonadal hormone 　　摘要：[目的]评估精索静脉曲张高位结扎术对精索静脉曲张致重度少精或无精患者的治疗效果。[方法] 精索静脉曲张致重度少精（精子密度小于2百万/毫升）或无精患者20例（其中前者12例、后者8例，伴阴囊坠胀感共有5例）为实验组，术前（术前3天内）精液分析和血清性腺激素（FSH、LH、T、E2和PRL）的变化分别与术后2月、4月、8月行对比分析。并选用10名精索静脉曲张致重度少精或无精且不同意手术患者作为对照组。[结果] 实验组患者术前和术后2月、4月、8月精液分析和性腺激素均无明显变化，差异无统计学意义（Pgt;0.05），实验组与对照组相比亦无统计学意义（Pgt;0.05）。但5例阴囊坠胀感患者不适症状均明显减轻或消失。 [结论] 本研究认为手术治疗对改善此类??者精液质量无明显效果，不建议对重度少精或无精，期望改善精液质量患者行手术治疗。 　　关键词：精索静脉曲张;精索静脉高位结扎术;治疗;精液质量;性激素 　　中图分类号：R 699.8 文献标识码：A 　　Varicocele （VC） is a common disease of