实时三平面超声心动图评价先天性心脏病手术前后左室收缩功能改变的初步研究-evaluation of left ventricular systolic function changes before and after congenital heart disease surgery by real-time three-plane echocardiography.docxVIP

安徽医科大学硕士学位论文 安徽医科大学硕士学位论文 PAGE PAGE 5 Instruments and methods GE Vivid7 Dimension-mode color ultrasound diagnostic apparatus equipped with real-time three-dimensional(RT-3D) ultrasound imaging and three-dimensional ultrasound probe (3V) ( frequency, 1.5～4.0MHz) was used in diagnosis . From June 2008 to January 2010, 57 patients (37 males and 20 females), aged 2～12 years (4.94±2.97) with congenital heart disease, of which 19 patients with atrial septal defect, 23 patients with ventricular septal defect and 15 patients with patent ductus arteriosus underwent operation.Real-time tri-plane Echocardiography (RT-3PE) was used to measure quantitatively left ventricular end-diastolic volume (LVEDV) and end-systolic volume (LVESV) to calculate left ventricle ejection fraction (EF) and stroke volume (SV) before surgery, 5～7 days and one month after surgery. Meanwhile，the functions of left ventricular ware evaluated with other two methods 2DE Simpson and MME to compare with RT-3PE.As control group, the functions of left ventricular in thirty normal subjects were measured by the above mentioned three methods (RT-3PE, 2DE Simpson and MME). Results (1)LVEDV, LVEDS and LVSV measured by three different methods were significantly different in any two methods (P 0.05), of which the values measured by MME were maximum , the values measured by 2DE biplane Simpson were minimum. LVEF showed no significant difference compared with 2DE. The values measured by the three methods were relevant. The values measured by RT-3PE and 2DE biplane Simpson showed good relationship (Normal group r = 0.869，CHD group r =0.914， P0.001), and the values measured by RT-3PE and MME also showed correlation (Normal group r =0.719，CHD group r =0.792, P 0.001). LVEDV, LVESV, LVSV and LVEF measured by RT-3PE in patients with ASD were lower than those in control group (P0.05). LVEDV, LVESV, LVSV and LVEF measured by RT-3PE 5～7 days after surgery in patients with ASD were higher than those in control group (P0.05