呼吸内科住院患者抗菌药物的临床选择与合理应用研究.docVIP

呼吸内科住院患者抗菌药物的临床选择与合理应用研究 　　摘要：目的 通过统计、分析我院呼吸内科住院患者抗生素的使用数量、类型来探讨呼吸内科住院患者抗菌类药物的临床选择及合理应用方式。方法 随机选取2015年1月～2016年1月我院呼吸内科住院患者300例作为本次研究的对象，对所有患者的临床资料进行回顾性分析，统计和分析患者应用抗菌类药物的类型、联合用药、不合理用药以及治疗效果，探讨呼吸内科抗菌药物临床选择与合理应用的情况。结果 在本次研究的300例患者中，共有287例患者应用抗菌类药物，占95.67%；其中使用比例较高的前三位为头孢他啶（42.62%）、头孢哌酮（34.18%）、阿莫西林（25.47%）；其中有163例一?用药，占54.29%；68例二联用药，占22.63%；59例三联用药，占19.82%；10例四联用药，占3.26%。存在不合理使用抗生素的情况共19例，占6.33%；患者治疗总有效率97.25%。结论 我院呼吸内科抗菌药物的临床选择与合理应用情况较好，医师能够彻底了解抗菌类药物效果、特点、适应症以及药物反应等来选择抗菌药物，减轻患者耐药性，提高患者生活质量，以此保证患者用药的安全和合理。 　　关键词：呼吸内科；住院患者；抗菌药物；合理应用 　　中图分类号：R969.3 文献标识码：A 文章编号：1006-1959（2017）18-0084-03 　　Abstract：Objective To analyze the number and types of antibiotics used in respiratory medicine department of our hospital and to investigate the clinical selection and rational application of antibiotics in respiratory medicine.Methods A total of 300 patients were admitted to our hospital from January 2015 to January 2016.The clinical data of all patients were analyzed retrospectively，to analyze the types of antibiotics used in patients，the combination therapy，irrational drug use and the therapeutic effect，to explore the clinical selection and rational application of antibiotics in respiratory medicine.Results In the study of 300 patients，a total of 287 patients with antibiotics，accounting for 95.67%；which use the higher proportion of the top three for ceftazidime（42.62%），cefoperazone（34.18%），amoxicillin（25.47%）；Of which 163 cases of a drug，accounting for 54.29%；68 cases of two drug， accounting for 22.63%；59 cases of triple therapy，accounting for 19.82%；10 cases of four drug accounted for 3.26%，the existence of irrational use of antibiotics in 19 cases，accounting for 6.33%；the total effective rate of patients in clinical 97.25%.Conclusion The clinical choice and reasonable application of antimicrobial agents in our hospital are good，the physician can thoroughly understand the antibacterial effect，characteristics，indications and drug reactions to select antibiotics，reduce patient r