ICU治疗对重症急性胰腺炎患者APACHEⅡ评分及生化指标影响.docVIP

ICU治疗对重症急性胰腺炎患者APACHEⅡ评分及生化指标影响 　　[摘要] 目的 探讨ICU治疗重症急性胰腺炎（SAP）的效果。 方法 选取本院2010年1月～2014年5月收治的109例SAP患者作为研究对象，随机分为对照组（55例）和研究组（54例）。对照组给予常规内科治疗，研究组在对照组的基础上给予ICU综合治疗，比较两组的住院时间、死亡率及并发症发生率、APACHE Ⅱ评分及MODS评分、治疗72 h后各项生化指标。 结果 研究组的死亡率及并发症发生率显著低于对照组，差异有统计学意义（P0.05）。研究组治疗后的APACHE Ⅱ评分及MODS评分均显著低于对照组，差异有统计学意义（P0.05）。研究组治疗后72 h的BUN、SCr、TBiL、ALT水平显著低于对照组，差异有统计学意义（P0.05）。 结论 ICU综合治疗SAP效果显著，能够有效降低死亡率及并发症发生率，改善患者的预后及生活质量，值得临床推广应用。 　　[关键词] 危重病的监护与治疗；重症急性胰腺炎；疗效 　　[中图分类号] R576 [文献标识码] A [文章编号] 1674-4721（2015）07（c）-0022-03 　　Influence of ICU treatment on APACHE Ⅱscore and biochemical indexes in patients with severe acute pancreatitis 　　ZHANG Guo-yu WANG Chun-xian 　　Department of Intensive Care Medicine，Pinggu Hospital of Beijing City Affiliated to Yanjing Medical College of Capital Medical University，Beijing 101200，China 　　[Abstract] Objective To explore the effect of ICU in the treatment of severe acute pancreatitis. Methods 109 cases with severe acute pancreatitis from January 2010 to May 2014 in our hospital were selected and randomly divided into the control group （55 cases） and the study group （54 cases）.The control group was given conventional internal medicine treatment，the study group was given ICU treatment on the basis of the control group.The hospital stay，mortality and incidence of complication，APACHE Ⅱscore and MODS score，biochemical indexes of 72 hours after treatment in two groups was compared. Results The mortality rate and the incidence rate of complication in the study group was lower than that in the control group，with significant difference（P0.05）.The score of APACHE ⅡMODS in the study group after treatment was lower than that in the control group，with significant difference（P0.05）.The level of BUN，SCr，TBiL，ALT in the study group after treatment at 72 hours was lower than that in the control group，with significant difference（P0.05）. Conclusion The effect of ICU in the treatment of severe acute pancreatitis is significant，which can effectively reduce the morta