TCT联合宫颈活检在早期宫颈癌诊断中作用探讨.docVIP

TCT联合宫颈活检在早期宫颈癌诊断中作用探讨 　　[摘要] 目的 探讨TCT联合宫颈活检在早期宫颈癌诊断中的作用。 方法 整群选取2013年1月―2014年1月在该院妇科门诊收诊的2303例宫颈检查患者，行宫颈薄层液基细胞学（TCT）检查，再对阳性患者进行宫颈活检组织病理检查，结合病检报告分析结果并作出诊断，其标准采用TBS分类系统。 结果 在2303例妇女中，未见上皮内病变/恶性细胞（NILM） 2217例（96.27%），阳性86例（3.73%），其中ASCUS 48例，LSIL 22例，HSIL 14例，SCC 2例。宫颈活检86例，其中宫颈黏膜慢性炎25例，CIN Ⅰ30例，CINⅡ 19例，CINⅢ 9例，SCC 3例。 结论 TCT联合宫颈活检不仅可显著提高宫颈癌的诊断率，更是早期宫颈癌诊断行之有效的可靠检查方法，具有广阔的临床应用前景。 　　[关键词] TCT；宫颈活检；早期宫颈癌；诊断 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2016）03（b）-0162-02 　　[Abstract] Objective To discuss the effect of TCT combined with cervical biopsy in diagnosis of early cervical cancer. Methods 2303 cases of patients with cervical biopsy admitted and treated in the gynecology clinic of our hospital from January 2013 to January 2014 were selected and were given TCT examination， and then the positive patients were given cervical histopathological examination， the diagnosis was made combined with the analysis Results of pathological examination report with the standard of TBS classification system. Results In the 2303 cases of women， 2217 cases were without intraepithelial lesion/ malignant cell （96.27%）， 86 cases were positive， among them， ASCUS was in 48 cases， LSIL was in 22 cases， HSIL was in 14 cases， SCC was in 2 cases， 86 cases received the cervical biopsy， among them， chronic cervical mucositis was in 25 cases， CINⅠwas in 30 cases， CINⅡwas in 19 cases， CIN Ⅲ was in 9 cases， SCC was in 3 cases. Conclusion TCT combined with cervical biopsy can not only obviously improve the diagnosis rate of cervical cancer but also is a feasible and reliable examination method of the diagnosis of early cervical cancer with a broad scope in future clinical application. 　　[Key words] TCT； Cervical biopsy； Early cervical cancer； Diagnosis 　　宫颈癌是最常见的妇科恶性肿瘤之一，近年来，宫颈癌的发生率逐步上升并有着年轻化的趋势，因此引起了广泛的关注。研究表明，通过宫颈癌的早期诊断，可大大降低宫颈癌的发生率[1-2]。传统的宫颈切片巴士涂片因其成本低廉，对设备要求较低在医院广泛使用，但是同时也受到标本满意度低、诊断准确度低的限制[3]。因此，迫切需要更敏感、准确的方法以有效地发现早期宫颈癌及癌前病变。液基细胞学检查（thinprepcytologiclest， TCT） 采用液基薄层细胞检测系统检测宫颈细胞并进行细胞学分类诊断，