三维适形放疗联合同步化疗治疗宫颈癌放疗后复发临床分析.docVIP

三维适形放疗联合同步化疗治疗宫颈癌放疗后复发的临床分析 　　[摘要] 目的 ?^察与探讨三维适形放疗联合同步化疗治疗宫颈癌放疗后复发的临床效果。 方法 选取2014年4月～2017年4月治疗的宫颈癌放疗之后出现复发的患者70例作为研究对象，根据随机方法分组，每组35例，对照组患者给予单纯化疗治疗，对观察组患者给予三维适形放疗联合同步化疗治疗，对比并分析两组患者的临床治疗效果、体重改变情况及不良反应状况。 结果 观察组患者的治疗总有效率（82.87%）与对照组患者（60.00%）比较，组间差异有统计学意义（P0.05）。 结论 对宫颈癌放疗后复发患者应用三维适形放疗联合同步化疗治疗的效果比较好，使患者病症得到显著改善，使患者的治疗总有效数据得到明显提升，增加患者的体重，并且没有明显增加患者的不良反应，具有一定的安全性，可进一步推广使用。 　　[关键词] 三维适形放疗；同步化疗；宫颈癌放疗后复发；宫颈癌；不良反应 　　[中图分类号] R737.33 [文献标识码] B [文章编号] 1673-9701（2017）30-0068-03 　　[Abstract] Objective To observe and explore the clinical effect of three-dimensional conformal radiotherapy combined with concurrent chemotherapy in the treatment of cervical cancer recurrence after radiotherapy. Methods 70 patients with recurrent cervical cancer after radiotherapy who were treated by the author from April 2014 to April 2017 were selected as the study subjects. According to randomized method， the patients were grouped， with 35 patients in each group. The patients in the control group were given chemotherapy alone， and the patients in the observation group were given three-dimensional conformal radiotherapy combined with concurrent chemotherapy. The clinical treatment effect， weight change and adverse reactions of the two groups of patients were analyzed and compared. Results The total effective rate of treatment in the observation group was 82.87%， compared with the control group（60.00%）， the difference between the two groups was statistically significant（P0.05）. Conclusion The effect of three-dimensional conformal radiotherapy combined with concurrent chemotherapy in patients with recurrence of cervical cancer after radiotherapy is better， so that the patients condition is improved significantly. The total effective data of treatment in patients has been significantly improved， and the patients body weight is increased. Patients adverse reactions of patients are not significantly increased， and the safety is favorable. Therefore， the treatment can be further applied and promoted