不同植骨材料配合LCP治疗尺桡骨骨折不愈合疗效研究.docVIP

不同植骨材料配合LCP治疗尺桡骨骨折不愈合的疗效研究 　　【摘要】 目的：比较自体骨、同种异体骨、BMP复合骨配合LCP治疗尺桡骨骨折不愈合的临床疗效。方法：选取2009年12月-2013年12月采用植骨配合LCP治疗尺桡骨骨折不愈合的62例患者，根据植骨材料不同分为自体骨组（A组，22例）、同种异体骨组（B组，23例）、BMP复合人工骨组（C组，17例）。比较不同时间点三组Anderson前臂骨折功能优良率及12个月后的治愈率。结果：A、B两组骨不连治愈情况比较差异有统计学意义（ 字2=5.494，P0.05）。A、B两组各时间段优良率比较差异均有统计学意义（P0.05）；9个月与12个月时，B、C组比较差异有统计学意义（P0.05）。结论：BMP复合骨在配合LCP治疗尺桡骨骨折不愈合中与自体骨基本等效，并优于同种异体骨。 　　【关键词】 锁定加压钢板； 尺桡骨骨折不愈合； BMP复合骨； 植骨材料 　　Comparison of Locking Compression Plate Combined with Three Different Bone Grafts for Nonunion of Radius and Ulna Fracture/WANG Hu-gen， XU Bin.//Medical Innovation of China，2015，12（12）：041-043 　　【Abstract】 Objective：To compare the effectiveness of locking compression plate combined with three different bone grafts autogenous bone， allogeneic bone，and bone morphogenetic protein （BMP） composite bone for radius and ulna fracture nonunion.Method：From December 2009 to December 2013， 62 cases of eligible of radius and ulna fracture nonunion were randomly treated with autogenous bone （group A， n=22）， allogeneic bone （group B， n=23）， and BMP composite bone （group C， n=17）.The cure rate after 12 months and the Anderson good rate of forearm fractures were compared among 3 groups at different time points.Result：All patients of 3 groups were followed up at least 12 months.The cure rate of groups A and B was signifcantly different （ 字2=5.494，P 0.05）.The Anderson good rate was compared at same period：There were significant difference between the group A and B of each time period （P0.05），but no significant difference was found between groups A and C； at 6th and 12th months after operation， there was significant difference between the group B and C （P0.05）.Conclusion：The effect of BMP composite bone is equivalent to that of autogenous bone graft in treating nonunion of radius and ulna fracture， and they are better than allogeneic bone graft. 　　【Key words】 Locking compression plate； Radius and ulna fracture nonunion； Bone morphogenetic protein composite bone； Bone grafts 　　F