中医药防治脓毒症研究进展.docVIP

中医药防治脓毒症的研究进展 　　[摘要] 脓毒症给医疗卫生行业和国家经济带来极大负担，且抗感染治疗所使用的抗生素也会造成耐药菌的产生、不良反应的发生，降低了疗效和患者的生活质量。但随着中医药治疗脓毒症的研究的不断深入，在减少耐药菌的产生、改变耐药菌或泛耐药菌的耐药性、预防多重感染的发生、应对炎症反应和免疫损害、治疗胃肠功能障碍和凝血功能紊乱等问题上，中医药的思路方法逐渐发挥其优势。近年来，随着临床研究的不断开展，关于中医药方法治疗脓毒症，尤其是血必净注射液的疗效得到广泛认可。除此之外，关于中成药、汤剂、针灸、穴位贴敷等方法治疗脓毒症的临床研究越来越多，对降低脓毒症患者的病死率、降低炎性指标、凝血指标起到重要作用。但因脓毒症的病理生理机制的不明确、病情进展迅速、耐药菌耐药的问题，我们的任务仍然艰巨。期待更多高质量的研究产生，也期待更加个体化、精细化的治疗方案的出现。 　　[关键词] 中医药；脓毒症 　　Research progress of traditional Chinese medicine in 　　prevention and treatment of sepsis 　　ZHAO Guo-zhen 1，2，3，GUO Yu-hong 1，LI Bo 1，3，HU Jing 1，3，CHEN Teng-fe1， 　　DI Hao-ran 1，2，3，SHAO Fei 1，2，3，LIU Qing-quan 1，3 　　（1. Beijing Hospital of Traditional Chinese Medicine，Capital Medical University，Beijing 100010，China； 　　2. Beijing University of Chinese Medicine，Beijing 100029，China； 　　3.Beijing Key Laboratory of Basic Research with Traditional Chinese Medicine on Infectious Diseases， 　　Beijing Insititute of Traditional Chinese Medicine，Beijing 100010，China） 　　[Abstract] Sepsis brings great burden to the industry of health care and national economy，and antibiotics used in anti-infective treatment will cause the emergence of drug-resistant bacteria，adverse reactions，and reduce the efficacy and quality of life. However，with the deepening of the study of traditional Chinese medicine treatment of sepsis，in reducing the production of drug-resistant bacteria，changing the drug resistance of drug-resistant bacteria，preventing multiple infection，response to inflammatory response and immune damage，treatment of gastrointestinal dysfunction and coagulation disorders，TCM is gradually exerting its advantages. In recent years，with the continuous development of clinical research，the curative effect of traditional Chinese medical way is widely recognized，especially Xuebijing injection. In addition，the clinical research of Chinese medicine，acupuncture，acupoint sticking is more and more. Its play an important role to reduce the mortality of patients with sepsis，reduce inflamma