中山地区住院患者RhD阴性血型分布特点与输血安全临床研究.docVIP

中山地区住院患者RhD阴性血型分布特点与输血安全的临床研究 　　[摘要] 目的 通过对中山市某三甲医院RhD阴性住院患者血型分布特点和用血情况进行调查分析，指导RhD阴性血液库存管理，保障RhD阴性患者临床输血安全。 方法 对本院2012年1月～2016年11月住院患者ABO及RhD血型资料进行统计分析。 结果 221 051例住院患者ABO血型分布特点为OBAAB，男女间ABO血型分布有统计学差异（P=0.004）；检出RhD阴性患者511例，占0.231%，其中A、B、AB、O型患者RhD阴性检出率分别为0.060%、0.060%、0.026%、0.087%，分布特点为OA=BAB。RhD阴性在ABO血型系统中的分布存在男女性别差异，RhD阴性血型在男性为OABAB，女性为OBAAB。221 051例住院患者中有13 983例输血患者，输血患者血型分布特点为OBAAB，RhD阴性输血患者有34例，占0.243%，其血型分布特点为OBAAB。 结论 RhD阴性血型住院患者和输血患者ABO血型分布特征基本一致，有利于当地血站对RhD阴性血液采集和储备。RhD阴性住院患者和输血患者占有一定比例，输血科应加强RhD阴性血液的库存管理，与血站做好协同合作，合理调配血液资源。 　　[关键词] ABO血型；RhD阴性血型；血型分布；库存管理；?血安全 　　[中图分类号] R446.1 [文献标识码] B [文章编号] 1673-9701（2017）34-0088-03 　　Clinical study on RhD negative blood type distribution and blood transfusion safety in inpatients of Zhongshan region 　　LIN Miaoxiong GU Xiangming PENG Ming WU Weiqiang DU Guoyou 　　Department of Blood Transfusion and Laboratory，Zhongshan Hospital of Traditional Chinese Medicine in Guangdong Province，Zhongshan 528400，China 　　[Abstract] Objective To guide RhD-negative blood inventory management and ensure the safety of clinical blood transfusion in RhD negative patients by analyzing the distribution of blood type and blood use status of RhD-negative inpatients in a top-three hospital in Zhongshan City. Methods The data of ABO and RhD inpatients from January 2012 to November 2016 in our hospital were statistically analyzed. Results The distribution characteristics of ABO blood type in 221 051 inpatients was OBAAB. There was a statistically significant difference in ABO blood group distribution between male and female patients（P=0.004）. 511 cases were detected with negative RhD， accounting for 0.231% The detection rates of types of A、B、AB、O patients with RhD negative type were 0.060%， 0.060%， 0.026% and 0.087%， respectively. The distribution characteristics of RhD negative type were OA=BAB.There was gender difference between men and women in the distribution of RhD negative blood group ABO system， with OABAB in men， OBAAB in women.