五项肾功能生化检测指标运用在诊断糖尿病肾功能损伤临床效果评价.docVIP

五项肾功能生化检测指标运用在诊断糖尿病肾功能损伤的临床效果评价 　　[摘要] 目的 研究在糖尿病肾功能损伤诊断中进行尿液标本尿N-乙酰-D-氨基葡萄糖苷酶（NAG）、尿微量白蛋白（MA），血清标本β2-微球蛋白（β2-MG）、胱抑素C（Cys C）、视黄醇结合蛋白（RBP）检测的价值。方法 在2016年9月―2017年9月方便选取该院100例糖尿病患者作为观察组，另外选取同期50名健康受检者作为对照组，收集全部研究对象的尿液样本以及血液样本，均进行NAG、β2-MG、Cys C、RBP、MA五项肾功能生化指标检测，分析检测结果。结果 相较于对照组，观察组各组的指标水平以及阳性率均明显更高（P0.05）；相较于NA组，MA组以及CP组各项指标水平以及阳性率均明显更高（P0.05）；相较于MA组，CP组各项指标水平以及阳性率均明显更高，CP组NAG、RBP、Cr、β2-MG、BUN、Cys C阳性率分别为51.72%、41.38%、41.38%、48.28%、44.83%、55.17%（P0.05）。结论 五项肾功能生化检测指标运用在糖尿病肾功能损伤诊断中能够帮助临床早期发现糖尿病肾功能损伤，有助于临床尽早实施治疗，改善患者预后。 　　[关键词] 糖尿病；肾功能损伤；生化检测指标；诊断 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2017）12（b）-0018-03 　　[Abstract] Objective To research the test value of NAG， MA， β2-MG， Cys C in diabetes renal function. Methods 100 cases of diabetes patients in our hospital from September 2016 to September 2017 were convenient selected as the observation group， besides， 50 cases of healthy examination people were used as the control group， and the urine samples and blood samples of all patients were collected for NAG， β2-MG， Cys C， RBP， MA test， and the test results were analyzed. Results The levels of various indicators and positive rate in the observation group were obviously higher than those in the control group（P0.05）， and the levels of various indicators and positive rate in the MA group and CP group were obviously higher than those in the NA group（P0.05）， and the levels of various indicators and positive rate in the CP group were obviously higher than those in the MA group， and the positive rates of NAG，RBP，Cr，β2-MG，BUN，Cys C in the CP group were respectively 51.72%，41.38%，41.38%，48.28%，44.83%，55.17%（P0.05）. Conclusion The application of five renal function biochemical test indicators in diagnosis of diabetes renal function injury can help the early discovery of diabetes renal function， which is conducive to early treatment and improvement of prognosis. 　　[Key words] Diabetes； Renal function injury； Biochemical test indicators； Diagnosis 　　糖尿病是由于不同?N因素共同作用导致的一类内分泌代谢类疾病，