匹多莫德辅助治疗儿童反复呼吸道感染应用体会.docVIP

匹多莫德辅助治疗儿童反复呼吸道感染应用体会 　　【摘要】 目的：探讨匹多莫德在儿童反复呼吸道感染中的应用价值。方法：选取2012年10月-2013年10月在笔者所在医院住院治疗的患儿120例为研究对象，将其随机分为两组，每组60例。对照组给予抗感染、化痰等常规治疗，试验组在对照组常规治疗的基础上加用匹多莫德分散片口服2个月，停药后随访6个月，观察两组疗效。结果：试验组总有效率93.3%，对照组为75.0%，两组比较差异有统计学意义（P0.05）。试验组发热天数、肺部??音消失时间、病程均较对照组明显短，差异均有统计学意义（P0.05）。结论：匹多莫德辅助治疗儿童反复呼吸道感染疗效显著，值得临床推广。 　　【关键词】 匹多莫德； 反复呼吸道感染； 儿童 　　中图分类号 R725.6 文献标识码 B 文章编号 1674-6805（2016）24-0107-02 　　【Abstract】 Objetive：To explore the value of Pidotimod in the treatment of children recurrent respiratory infection.Method：120 cases of recurrent respiratory infection children who were diagnosed and treated in our department from October 2012 to October 2013 were selected as the objects and randomly divided into two groups，60 cases in each group.The control group received the conventional treatment such as anti-infection and spasmolysis，the experimental group received conventional treatment plus Pidotimod disket for 2 months，the curative effect of the two groups were observed after followed up for six months.Result：The total effective rate of the experimental group was 93.3%，which was 75.0% of the control group，the difference was statistically significant（P0.05）.Compared with the control group，the fever clearance time，the disappearance time of pulmonary rales and the course of disease were significantly decreased in the experimental group，the differences were statistically significant（P0.05）.Conclusion：As an adjuvant therapy，the therapeutic effect of Pidotimod is obvious for the recurrent respiratory infection，it is worthy of clinical promotion. 　　【Key words】 Pidotimod； Recurrent respiratory infection； Child 　　First-author’s address：Jingzhou Center Hospital，Jingzhou 434020，China 　　doi：10.14033/ki.cfmr.2016.24.060 　　反复呼吸道感染（RRI）是儿科常见疾病，好发于学龄前儿童，发病率随着年龄的增长逐渐降低。由于小儿正处于生长发育过程中，呼吸及免疫系统尚未发育成熟，抵御病原微生物的能力较差，容易出现反复呼吸道感染，如果不及时治疗，往往有向慢性化发展的倾向。匹多莫德是人工合成的免疫增强剂，可显著减少呼吸道感染的次数[1]。本研究采用随机对照的方法，观察了反复呼吸道感染患儿口服匹多莫德的临床疗效，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选取2012年10月-2013年10月在笔者所在医院住院治疗的患儿120例为研究对象，所有患