初诊2型糖尿病合并非酒精性脂肪肝脂肪含量相关因素研究.docVIP

初诊2型糖尿病合并非酒精性脂肪肝脂肪含量的相关因素研究 　　[摘要] 目的 研究初?\2型糖尿病合并非酒精性脂肪肝脂肪含量的相关因素。 方法 选取2014年6月～2015年6月我院90例初诊2型糖尿病患者为研究对象，合并组患者为45例2型糖尿病合并非酒精性脂肪肝患者，对照组患者为45例2型糖尿病且无其他病症，分别测定BMI、WHR、FBG、HDL-C、LDL-C、GH、FINS、TC、TG指标水平。结果 两组患者在肥胖、超重、高血压、高TC及高TG指标方面，合并组的每项患病率均高于对照组，尤其在超重及高TG两项更加显著，差异有统计学意义（χ2=9.5255，P=0.0020；χ2=9.6797，P=0.0019）；合并组患者的BMI、WHR、FBG、HDL-C、LDL-C、GH、FINS每项指标均明显高于对照组，尤其在BMI、HDL-C、LDL-C及GH水平分别为（27.4±3.4）kg/m2、（1.25±0.34）mmol/L、（2.72±0.21）mmol/L、（12.50±1.41）%，差异有统计学意义（t=8.9195，P=0.0000；t=2.0411，P=0.0442；t=7.1857，P=0.0000；t=12.6289，P=0.0000）；合并组患者TC、TG指标水平分别为（6.25±1.62）mmol/L、（3.35±0.91）mmol/L，均显著高于对照组，尤其是TG更加明显，差异有统计学意义（t=2.5284，P=0.0132；t=3.1841，P=0.0020）。结论 初诊2型糖尿病合并非酒精性脂肪肝患者的脂肪含量与BMI、GH、TC、TG等因素相关，可提供有效的早诊断早发现标准，减缓患者病情恶化。 　　[关键词] 2型糖尿病；非酒精性脂肪肝；脂肪含量；相关因素 　　[中图分类号] R587.1；R575.5 [文献标识码] A [文章编号] 1673-9701（2017）09-0020-03 　　Study on the relevant factors of fat content in newly diagnosed type 2 diabetes mellitus complicated with nonalcoholic fatty liver 　　ZHENG Lequn LU Xiang ZHANG Te 　　Department of Endocrinology， Wenzhou Hospital of TCM in Zhejiang Province， Wenzhou 325000， China 　　[Abstract] Objective To study the relevant factors of fat content in newly diagnosed type 2 diabetes mellitus complicated with nonalcoholic fatty liver. Methods 90 patients with newly diagnosed type 2 diabetes mellitus who were diagnosed in our hospital from June 2014 to June 2015 were selected as the study subjects. 45 patients in the combined group were with type 2 diabetes complicated with nonalcoholic fatty liver. 45 patients in the control group were with type 2 diabetes without complications. The levels of BMI， WHR， FBG， HDL-C， LDL-C， GH， FINS， TC and TG were measured respectively. Results From the indices of obesity， overweight， hypertension， high TC and high TG indices in the two groups， the prevalence rate of each index in the combined group was significantly higher than that in the control group， especially in overweight and high TG. There were significant differences between the