医院抗菌药物合理使用现状及管理对策研究.docVIP

医院抗菌药物合理使用现状及管理对策研究 　　【摘要】 目的：探究医院抗菌药物的合理使用现状及管理对策。方法：收集2012年3-5月到本院进行治疗的患者1000例并按照患者的入院顺序分为观察组和对照组，每组500例。对观察组制定抗菌药物的使用及实施细则，制作预防用药的方案，并成立专门管理抗菌药物的小组，调查患者的菌群，对质量进行定期的控制检查并与奖惩挂钩；对照组患者则进行常规的管理。结果：观察组管理后的住院及门诊抗菌药物总使用率（36.00%）较管理前（78.00%）明显降低；管理后，观察组的总用药率（36.00%）明显低于对照组（62.00%），两组比较差异均有统计学意义（P0.05）。结论：预防用药的方案详细化、组织机构的有效性、具体的抗菌药物的使用方法和实施细则及质量控制和奖惩挂钩等方法，是医院进行抗菌药物管理的重点。 　　【关键词】 合理用药； 抗菌药物； 用药率； 药物管理 　　【Abstract】 Objective：To explore the present situation and Management Countermeasures of the rational use of antimicrobial drugs.Method：100 patients in our hospital from March to May 2012 were selected and divided into two groups，50 cases in each group.The observation group was given the following treatment：formulated the detailed rules for the use of antimicrobial drugs，made programs for drug prevention，established a group for the specialized management of antibiotics，investigated the patient’s flora，checked quality regularly and linked it to the rewards and punishment.The control group was given routine management.Result：In the observation group，the total rate of the hospitalization and outpatient drug use after the management was significantly lower than before，after the management，the total rate of drug use in the observation group was significantly lower than that of the control group，the differences were statistically significant （P0.05）.Conclusion：The detail of drug prevention programs，the effectiveness of the organization，the methods and detailed implementation rules of antibacterial drugs，the control of the quality and the rewards and punishment linked to the management are the key points in the manage of antibacterial drugs. 　　【Key words】 Rational drug use； Antibiotics； Prescription rate； Drug Administration 　　First-author’s address：Petrochemical Hospital of Maoming City，Maoming 525000，China 　　doi：10.3969/j.issn.1674-4985.2015.17.040 　　抗菌药物已成为临床上应用最广泛、最多的药物[1-2]。但在我国，临床上抗菌药物的的滥用现象非常的严重。因不合理的使用，致使我国成为了世界细菌耐药最严重国家之一，相应的增加了病原性疾病的发生[3-4]。国家卫生部也针对这一事件积极采取措施，加强整治[