右美托咪定混合地佐辛和罗哌卡因在剖宫产术后患者自控硬膜外镇痛效果中临床分析.docVIP

右美托咪定混合地佐辛和罗哌卡因在剖宫产术后患者自控硬膜外镇痛效果中临床分析 　　[摘要] 目的 探?右美托咪定混合地佐辛和罗哌卡因在剖宫产术后患者自控硬膜外镇痛效果中的临床效果。方法2012年8月―2016年7月方便选择在该院实施剖宫产的术后产妇172例，根据随机数字表法分为对照组与观察组各86例，两组都给予基于罗哌卡因的腰硬联合麻醉，对照组给予地佐辛辅助自控硬膜外镇痛，观察组给予右美托咪定混合地佐辛辅助自控硬膜外镇痛，记录镇痛效果与不良反应发生情况。结果 所有产妇在术后镇痛期间呼吸、心率均在正常范围内波动，组间与组内对比都差异无统计学意义（P0.05）。观察组术后2、4 h与24 h的疼痛评分分别为（1.92±1.22）分、（1.67±0.89）分和（1.32±0.45）分，都明显低于对照组的（3.34±1.09）分、（2.29±0.44）分和（1.98±0.67）分，差异有统计学意义（P0.05）。结论 地佐辛和罗哌卡因混合应用右美托咪定在剖宫产术后的自控硬膜外镇痛中，使产妇循环功能保持稳定，镇痛、镇静效果提高，不良反应发生率未见增加，对产妇术后恢复有很好的促进作用。 　　[关键词] 剖宫产；自控硬膜外镇痛；右美托咪定；地佐辛；罗哌卡因 　　[中图分类号] R719 [文献标识码] A [文章编号] 1674-0742（2017）12（a）-0119-04 　　[Abstract] Objective To study the clinical effect of dexmedetomidine and dezocine and ropivacaine in the patient-controlled epidural analgesia of patients after the cesarean section. Methods 172 cases of delivery women after the cesarean section in our hospital from August 2012 to July 2016 were convenient selected and randomly divided into two groups with 86 cases in each， both groups adopted the combined spinal and epidural anesthesia based on the ropivacaine， while the control group adopted the dezocine assisted by patient-controlled epidural analgesia， and the observation group adopted the dexmedetomidine and dezocine assisted by patient-controlled epidural analgesia， and the analgesia effect and occurrence of adverse reactions were recorded. Results The breathing and heart rate of all delivery women after surgery fluctuated in the normal range， and the differences were not statistically significant（P0.05）， and the pain scores at 2 h， 4 h and 24 h after surgery in the observation group were obviously lower than those in the control group，[（1.92±1.22）points，（1.67±0.89）points，（1.32±0.45）points vs （3.34±1.09）points，（2.29±0.44）points，（1.98±0.67）points]（P0.05）. Conclusion The dexmedetomidine and dezocine and ropivacaine in the patient-controlled epidural analgesia of patients after the cesarean section can stabilize the circulation function of delivery women， improve the analgesic