原发性高血压患者两种主要中医体质对比研究.docVIP

原发性高血压患者两种主要中医体质对比研究 　　【摘要】 目的 研究?Ρ仍?发性高血压患者的两种主要中医体质与其发生发展的内在关系。方法 采取整群抽样法选取900例阴虚质原发性高血压患者作为阴虚组、900例痰湿质原发性高血压患者作为痰湿组， 采集两组患者的基本信息、个人健康信息， 对比两组患者的体格检查、实验室检查、靶器官损害辅助检查指标的水平。结果 痰湿组患者的体质量指数、腹围高于阴虚组， 差异具有统计学意义 （t=26.399、19.849， P0.05）。痰湿组患者的甘油三酯、空腹血糖、血尿酸均高于阴虚组， 差异具有统计学意义 （t=40.342、24.991、20.895， P0.05）。痰湿组患者的24 h尿蛋白低于阴虚组， 颈动脉内中膜厚度高于阴虚组， 左室射血分数低于阴虚组， 差异具有统计学意义 （t=22.027、23.387、19.844， P0.05）。结论 阴虚质、痰湿质原发性高血压患者的临床特点各不相同， 临床上治疗原发性高血压患者可根据其中医体质辨证分型实施有针对性的治疗， 以提高原发性高血压患者的血压控制效果。 　　【关键词】 原发性高血压；中医体质；阴虚质；痰湿质 　　DOI：10.14163/j.cnki.11-5547/r.2017.13.008 　　【Abstract】 Objective To study and compare the internal relation of occurrence and development of two main constitutions of traditional Chinese medicine in primary hypertension patients. Methods A total of 900 Yin deficiency of primary hypertension as Yin deficiency group and 900 phlegm-dampness of primary hypertension as phlegm-dampness group. Collection were made on basic information and personal health information in two groups， and comparison were made on physical examination， laboratory examination and target organ damage of auxiliary examination index levels in two groups. Results The phlegm-dampness group had higher body mass index and abdominal girth than Yin deficiency group， and the difference had statistical significance （t=26.399， 19.849， P0.05）. The phlegm-dampness group had higher triglycerides， fasting blood glucose and blood uric acid than Yin deficiency group， and the difference had statistical significance （t=40.342， 24.991， 20.895， P0.05）. The phlegm-dampness group had lower 24 h urine protein than Yin deficiency group， higher carotid intima-media thickness than Yin deficiency group， and lower left ventricular ejection fraction than Yin deficiency group. Their difference had statistical significance （t=22.027， 23.387， 19.844， P0.05）. Conclusion Yin deficiency and phlegm-dampness of primary hypertension patients have different clinical characteristics， and constitution of TCM syndrome differentiation shou