地衣芽孢杆菌活菌胶囊治疗婴幼儿呼吸道感染继发腹泻效果及安全性分析.doc

地衣芽孢杆菌活菌胶囊治疗婴幼儿呼吸道感染继发腹泻效果及安全性分析 　　[摘要] 目的 探讨地衣芽孢杆菌活菌胶囊治疗婴幼儿呼吸道感染继发腹泻的效果及安全性。 方法 选择2013年1～9月浙江省临安市人民医院儿科的呼吸道感染继发腹泻婴幼儿90例，随机分为实验组与对照组。两组患儿均予以常规治疗，包括补液保持水电解质及酸碱平衡、蒙脱石散止泻、保护胃肠黏膜等。实验组患儿加用地衣芽孢杆菌活菌胶囊，0.25 g/次，3次/d，疗程7 d。观察两组患儿治疗后每日腹泻次数和腹泻持续时间，并比较其治疗效果及安全性。 结果 治疗7 d后，实验组患儿每日解大便次数及腹泻持续时间明显少于对照组（P 0.05）。 结论 地衣芽孢杆菌治疗呼吸道感染继发腹泻的疗效确切，安全性较好，能有效调节患儿的肠道菌群紊乱，减少腹泻次数及腹泻持续时间。 　　[关键词] 微生态制剂；婴幼儿；呼吸道感染；继发腹泻；疗效 　　[中图分类号] R725.6 [文献标识码] A [文章编号] 1673-7210（2014）02（b）-0070-03 　　Curative effect and security analysis of Live Bacillus Licheniformis Granules on infants′ secondary diarrhea due to respiratory tract infection 　　CHEN Xiaosa1 HU Wenhui2 　　1.Department of Paediatrics， Lin′an People′s Hospital of Zhejiang Province， Lin′an 311300， China； 2.Department of Paediatrics， Taizhou Hospital of Zhejiang Province， Taizhou 317000， China 　　[Abstract] Objective To discuss curative effect and security analysis of Live Bacillus Licheniformis Granules on infants′ secondary diarrhea due to respiratory tract infection （RTI）. Methods 90 cases of infants with secondary diarrhea due to RTI from January to September 2013 collected by Lin′an People′s Hospital of Zhejiang Province were selected and divided into experimental group and control group at random. The infants in two groups were both given routine medical treatment， including： maintaining water-electrolyte and acid-base balance， antidiarrheal by montmorillonite powder， protecting the gastrointestinal mucosa and etc. The infants in experimental group were additionally given the Live Bacillus Licheniformis Granules， 0.25 g per time， three times a day for 7 days′ course of treatment. The daily diarrhea times and lasting time of infants in two groups after medical treatment were observed， and curative effect and security of infants in two groups were evaluated and compared as well. Results After 7 days′ medical treatment， daily defecate times and diarrhea lasting time of infants in experimental group were much less and shorter than those in contr