基于社会网络研究134例胃食管反流病中医证候分析.docVIP

基于社会网络研究134例胃食管反流病中医证候分析 　　摘要：目的 分析胃食管反流病的中医证候及临床表现，总结其在证候及症状方面的特点。方法 收集134例胃食管反流病病例，通过社会网络研究的中心性、凝聚子群等分析方法，根据得到的数据及图表，对其证候和症状的分布特点进行总结概括。结果 所有病例共出现72个症状、17个证候，其中反酸、烧心是其主要症状，其他症状以实证为主，肝胃不和、湿热内蕴、肝郁脾虚、肝胃郁热、脾胃虚弱是其主要证候，气滞、湿阻、气虚是其主要病机，肝、脾、胃是其主要病位。结论 胃食管反流病的中医证候和症状表现均呈现一定的复杂性和多元性，尚需进一步探究。 　　关键词：胃食管反流病；证候；症状；社会网络分析 　　DOI：10.3969/j.issn.1005-5304.2015.12.008 　　中图分类号：R259.7 文献标识码：A 文章编号：1005-5304（2015）12-0030-04 　　Analysis of TCM Syndromes of 134 Patients with Gastroesophageal Reflux Disease Based on Social Network BI Hong-yan， WANG Feng-yun， LI Zhen-hua， TANG Xu-dong （Xiyuan Hospital， China Academy of Chinese Medical Sciences， Beijing 100091， China） 　　Abstract：Objective To analyze TCM syndromes and clinical manifestations of gastroesophageal reflux disease （GERD）；To summarize its features in terms of syndromes and symptoms. Methods Totally 134 GERD patients were involved in the research. According to the data and charts from the methods of social network， like centrality and cohesive subgroup， the distribution characteristics of the syndrome and symptoms were summarized. Results There were 72 symptoms and 17 syndromes in the cases. Acid regurgitation and heart burn were the main symptoms， and most of the symptoms were excessive syndrome. The main syndromes included liver-stomach disharmony， endoretention of damp heat， liver-qi stagnation and spleen deficiency， stagnant heat of liver and stomach， and spleen-stomach weakness. Qi stagnation， dampness retention， and qi deficiency were the main pathogenesis. Liver， spleen， and stomach were the main locations of GERD. Conclusion TCM syndromes and symptoms of GERD showed the complexity and diversity， so further researches would be needed. 　　Key words：gastroesophageal reflux disease；TCM syndrome；symptom；social network 　　胃食管反流病（gastroesophageal reflux disease， GERD）是临床常见病，我国发病率约为5%～10%[1]。反酸、烧心为其主要表现，可同时伴有胸骨后灼痛、胸闷、咳嗽、咯痰、心悸等症状，严重者可影响饮食和睡眠。中医辨证论治GERD取得了很好的疗效[2-3]。GERD的辨证分型可有效指导临床，而目前对其中医证候研究数量不多，研究方法多局限于在既有诊断标准下对症状和证候频次和构成比的统