奥曲肽联合奥美拉唑在急性上消化道出血患者中应用效果分析.docVIP

奥曲肽联合奥美拉唑在急性上消化道出血患者中应用效果分析 　　[摘要] 目的 探讨奥曲肽联合奥美拉唑在急性上消化道出血患者中的应用效果。 方法 选取2015年10月～2016年11月在我院进行治疗的急性上消化道出血患者82例，按随机数字表法分为两组，对照组采用奥美拉唑治疗，观察组给予奥曲肽联合奥美拉唑治疗，比较两组平均止血时间和住院时间、止血率和再出血率、疗效及不良反应情况。 结果 与对照组比较，观察组止血时间及住院时间明显缩短，再出血率明显降低，差异有统计学意义（P0.05）。 结论 在急性上消化道出血患者治疗过程应用奥曲肽联合奥美拉唑治疗效果显著，可缩短止血时间，降低再出血率，促进患者康复。 　　[关键词] 奥曲肽；奥美拉唑；急性；上消化道出血；应用效果 　　[中图分类号] R573.2 [文献标识码] A [文章编号] 2095-0616（2017）07-66-03 　　Analysis on application effect of octreotide combined with omeprazole on acute upper gastrointestinal hemorrhage 　　HUANG Yin 　　Gaungdong Nongken Central Hospital，Zhanjiang 524002，China 　　[Abstract] Objective To explore the application effect of octreotide combined with omeprazole on acute upper gastrointestinal hemorrhage. Methods 82 patients with acute upper gastrointestinal hemorrhage who were treated in our hospital from October 2015 to November 2016 were selected and they were divided into two groups by random number table.The control group was treated with omeprazole and the observation group was treated with octreotide combined with omeprazole.The mean hemostatic time， hospital stay，hemostatic rate，recurrent bleeding rate，efficacy and adverse reactions of two groups were compared. Results Compared with the control group，the hemostatic time and hospital stay of observation group were significantly shortened and the recurrent bleeding rate was significantly decreased.Differences were statistically significant （P0.05）. Conclusion Octreotide combined with omeprazole in treatment of patients with acute upper gastrointestinal hemorrhage has a significant effect，which can shorten hemostatic time，decrease the recurrent bleeding rate and promote patients rehabilitation. 　　[Key words] Octreotide；Omeprazole；Acute；Upper gastrointestinal hemorrhage；Application effect 　　急性上消化道出血是一种较为常见的消化科急重症，急性胃黏膜损害、食管胃底静脉曲张、胃癌、消化性溃疡等为常见的病因，以呕血、黑便或血便等为主要表现[1]。急性上消化道出血可发生在各个年龄段，具有病情急、出血量大等特点，若无法及时进行治疗，易引发休克，严重将危及患者生命[2]。奥美拉唑是临床治疗急性上消化道出血的常用药物，可较好的治疗上消化道出血，但单独用药存在一定局限性[3]。本研究为探讨奥曲肽联合奥美拉唑在急性上消化道出血