宫腔镜联合去氧孕烯炔雌醇片治疗药物流产不全预防宫腔粘连临床研究.docVIP

宫腔镜联合去氧孕烯炔雌醇片治疗药物流产不全预防宫腔粘连临床研究 　　【摘要】 目的：探讨宫腔镜联合去氧孕烯炔雌醇片治疗药物流产不全预防宫腔粘连的可行性。方法：将笔者所在医院2013年6月-2014年4月考虑药物流产不全的120例患者随机分成试验组和对照组，试验组在宫腔镜下清宫，术后给去氧孕烯炔雌醇片口服，对照组行常规清宫术。术后观察阴道流血时间、首次月经恢复时间、月经量及有无周期性腹痛、子宫内膜的情况，宫腔镜检查是否宫腔粘连及粘连的程度。结果：试验组阴道流血时间（5.3±1.4）d，短于对照组的（7.3±2.5）d，差异有统计学意义（P0.05 ）；试验组首次月经恢复时间（27.6±4.6）d，短于对照组（36.6±6.8）d，差异有统计学意义（P0.05）；试验组术后经量减少、闭经、周期性腹痛、宫腔粘连的发生率（2.5%、0、2.5%、2.5%）低于对照组（12.5%、2.5%、12.5%、10.0%），差异均有统计学意义（P0.05）。结论：宫腔镜联合去氧孕烯炔雌醇片治疗药物流产不全，降低了子宫内膜的损伤，促进子宫内膜的修复，减少了子宫内膜炎症的发生，从而减少宫腔粘连的发生，是一种简单、安全、有效的技术，值得推广。 　　【关键词】 药物流产不全； 宫腔镜； 去氧孕烯炔雌醇片； 宫腔粘连 　　中图分类号 R714.21 文献标识码 B 文章编号 1674-6805（2016）5-0028-02 　　【Abstract】 Objective：To explore the feasibility of the prevention of intrauterine adhesion（IUA） through the clinical study on the treatment of abortion incompleteness by Desogestrel and Ethinylestradiol Tablets combined with hysteroscopy.Method：120 cases of abortion incompleteness received by the Maternal and Child Care Hospital（MCH） from June 2013 to April 2014 were randomly divided into the treatment group and the control group.The treatment group was given intrauterine residual tissues removal operation under hysteroscopy followed by oral dose of Desogestrel and Ethinylestradiol Tablets，while the control group was given just routine intrauterine residual tissues removal operation.Postoperative focused on time of vaginal bleeding，menstrual recovery，menstrual quantity and any cyclical abdominal pain，endometrial condition，any IUA or the degree of adhesion by hysteroscopy check were observed.Result：The time of vaginal bleeding in the treatment group was （5.3±1.4）d，which was shorter than （7.3±2.5）d in the control group；the first menstrual recovery time in the treatment group was （27.6±4.6）d which was shorter than （36.6±6.8）d in the control group.The treatment group experienced a reduction in menstrual quantity，amenorrhea，periodic abdominal pain，the percentage of IUA in the treatment group（2.5%，0，2.5%，2.5%） were better than the control group（12.5%，2.5%，12.5%，10.0%），