注射用他唑巴坦钠哌拉西林钠治疗新生儿感染120例临床分析.docVIP

注射用他唑巴坦钠哌拉西林钠治疗新生儿感染120例临床分析 　　摘要：目的：探究注射用他唑巴坦钠/哌拉西林钠治疗新生儿感染的临床治疗效果。方法：选取我院2012年7月～2014年7月住院部120例新生儿感染患者作为研究对象，按照治疗方法的不同将其分为实验组和对照组，实验组患者予以注射用他唑巴坦钠/哌拉西林钠治疗，对照组患者予以青霉素G钠治疗，观察两组患者临床治疗效果、细菌清除率、不良反应情况。结果：两组患者治疗后临床总有效率与细菌总清除率比较，实验组均明显高于对照组，p0.05，差异具有统计学意义；两组患者治疗后总不良反应率比较，实验组明显低于对照组，p0.05，差异具有统计学意义。结论：采用注射用他唑巴坦钠/哌拉西林钠治疗新生儿感染具有显著的临床疗效，细菌清除率高，且不良反应少，安全性高，值得临床应用以及推广。 　　关键词：他唑巴坦钠；哌拉西林钠；新生儿感染；疗效 　　Abstract ： objective to explore he thiazole ba jotham sodium for injection/piperacillin sodium clinical treatment effect for the treatment of neonatal infections. Selection method from July 2012 to July 2012 the inpatient 120 newborns infected patients as the research object， according to the treatment of the different divided into experimental group and control group， experimental group patients give he thiazole ba jotham sodium for injection/piperacillin sodium treatment， control group patients give penicillin G sodium treatment， to observe the clinical therapeutic effect， two groups of patients bacterial clearance rate， adverse reactions. Results the two groups after treatment in patients with clinical total effective rate and the total bacterial clearance rate comparison， the experimental group were significantly higher than that of control group， p 0.05， the difference is statistically significant； Total rate of adverse reactions after treatment in both groups， the experimental group significantly lower than the control group， p 0.05， the difference is statistically significant. Conclusion he thiazole ba jotham sodium for injection/piperacillin sodium treatment of neonatal infection has significant clinical efficacy， bacterial clearance rate is high， and less adverse reaction， high safety， worthy of clinical application and promotion. 　　key words： he azole sodium temple； Piperacillin sodium； Neonatal infection； The curative effect 　　新生儿感染（Neonatal infections）是新生儿期由于致病微生物引发的一种新生儿的炎症性疾病，临床症状和病原体的数量、侵入途径、毒力、新生儿胎龄、体重、营养状况、免疫状态等因素有关。宫内以及产时感染大部分在7天内发病，而生后感染多数在7天及以后发病[1]。而新生儿感染