注射用盐酸头孢甲肟治疗老年泌尿生殖系统感染合并糖尿病患者临床疗效观察.docVIP

注射用盐酸头孢甲肟治疗老年泌尿生殖系统感染合并糖尿病患者临床疗效观察 　　[摘要] 目的 研究注射用盐酸头孢甲肟老年泌尿生殖系统合并糖尿病患者的临床疗效。方法 收集由2012年4月―2015年5月期间诊治的老年泌尿生殖系统感染合并糖尿病患者150例，采用随机平均分配方式将150例划分为对照组和实验组，先对照组和实验组中的两组患者控制血糖，行皮下注射胰岛素治疗，实验组中的75例患者采用盐酸头孢甲肟治疗，行上肢静脉滴注，对照组中的75例患者采用左氧氟沙星治疗，行上肢静脉滴注。结果 实验组治疗有效率为94.67%（71/75），对照组有效率为78.67%（59/75），差异有统计学意义（P0.05）。实验组细菌学疗效转阴率为88.67%（65/75）；对照组细菌学疗效转阴率为66.67%（50/75），差异有统计学意义（P0.05）。结论 盐酸头孢甲肟在临床效果显著，细菌清除效果好，值得在临床推广和应用。 　　[关键词] 盐酸头孢甲肟；泌尿生殖系统；老年糖尿病 　　[中图分类号] R691.3 [文献标识码] A [文章编号] 1672-4062（2016）12（b）-0017-02 　　[Abstract] Objective To investigate the clinical efficacy of Hydrochloride injection Cefmenoxime in elderly patients with genitourinary infection and diabetes mellitus. Methods 150 patients with genitourinary infection and diabetes mellitus in our hospital between April 2012 and May 2015 were randomly divided into control group and experimental group with each 75 cases. First the two patients were to control blood sugar by row subcutaneous insulin therapy. The patients in experimental group were given hydrochloric acid Cefmenoxime therapy and the patients in control group were given levofloxacin therapy. Results The effective rate of experimental group was 94.67%（71/75） and the control group was 78.67%（59/75）， the difference was statistically significant （P0.05）. The bacteriological efficacy negative rate of experimental group was 88.67% （65/75） and control group was 66.67%（50/75）， the difference was statistically significant（P0.05）. Conclusion Cefmenoxime hydrochloride in treatment of patients with genitourinary infection and diabetes mellitus can significantly get clinical effect and the good bacteria scavenging effect， which is worthy of clinical application. 　　[Key words] Cefmenoxime hydrochloride； Urogenital system； Elderly diabetic patients 　　我??当前糖尿病中老年患者所占比例高，老年患者本身免疫机制差，抵抗力弱，老年糖尿病患者尿液中含糖量高，这两个因素加一块更容易造成泌尿生殖系统感染，感染率大大提高，对老年患者的身体健康造成了严重的威胁和影响，临床上对老年糖尿病合并泌尿生殖系统患者长采用提前预防或药物缓解治疗方案[1-2]。盐酸头孢甲肟为第二代半合成抗生素，对葡萄球菌、肠杆菌、大肠埃希菌等革兰阳性菌和革兰阴性菌均有较强的抗菌活性，对泌尿系统感染治疗有很大的帮助[3]。该文针对盐酸头孢