活性维生素D3治疗对维持性血透患者左心室肥厚影响分析.docVIP

活性维生素D3治疗对维持性血透患者左心室肥厚影响分析 　　【摘要】 目的 观察探讨活性维生素D3治疗对维持性血透患者左心室肥厚的影响。方法 回顾性分析我院和郴州市第一人民医院从2010年1月—2012年5月期间所收治的伴继发性甲状旁腺功能亢进的维持性血透患者98例，随机将其分为观察组和对照组各49例，其中观察组使用活性维生素D3治疗，对照组使用常规治疗，观察两组的临床治疗效果。结果 观察组经过活性维生素D3治疗后，显效有22例，有效有21例，无效有6例，其总有效率为87.8%；对照组经过常规治疗后，显效有12例，有效有17例，无效有20例，其总有效率为59.2%；两组比较差异显著（p0.05），具有统计学意义。结论 使用活性维生素D3治疗对维持性血透患者的治疗效果理想，对左心室肥厚的指标明显降低，能够有效地降低患者的不良反应和并发症，且后遗症低，值得临床推广使用。 　　【关键词】 血透；左心室肥厚；活性维生素D3；临床效果 　　doi：10.3969/j.issn.1004—7484（x）.2012.08.014 文章编号：1004—7484（2012）—08—2408—01 　　【Abstract】Objective To evaluate the activity of vitamin D3therapy on maintenance hemodialysis patients with left ventricular hypertrophy and the effect analysis.Methods Retrospective analysis of our hospital and the Chenzhou First Peoples Hospital from 2010January —2012 year in May during treatment with secondary hyperparathyroidism in maintenance hemodialysis patients with 98 cases，randomly divided into the observation group and the control group with 49 cases in each group，the observation group used active vitamin D3treatment，the control group using conventional treatment，observation on clinical therapeutic effect of two groups.Results The observation group after active vitamin D3treatment，effective in 22 cases，effective in 21 cases，ineffective in 6 cases，the total effective rate was 87.8%；the control group after conventional treatment，effective in 12 cases，effective in 17 cases，ineffective in 20 cases，the total effective rate was 59.2%；in two groups comparison of difference significant （p0.05），with statistical significance.Conclusion The use of active vitamin D3treatment in patients on maintenance hemodialysis treatment effect is ideal，on left ventricular hypertrophy index decreased significantly，can effectively reduce the patients with adverse reactions and complications，and sequelae of low，is worthy of clinical use. 　　【Key words】 Hemodialysis left ventricular hypertrophy active vitamin D3 clinical effect 　　血透是血液透析的简称，它是一种血液净化技术，是利用半透膜原理，通过弥散、对流等方式清除体内各种有害以及多余的代谢废物和过多的电解质