γ-干扰素释放试验在不明病因类型反复发作葡萄膜炎病因诊断中的临床应用初步研究-眼科学专业论文.docxVIP

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γ-干扰素释放试验在不明病因类型反复发作葡萄膜炎病因诊断中的临床应用初步研究-眼科学专业论文.docx

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γ-干扰素释放试验在不明病因类型反复发作葡萄膜炎病因诊断中的临床应用初步研究-眼科学专业论文

万方数据万方数据目录中文摘要·········································································································1 英文摘要·········································································································4 英文缩写·········································································································8 研究论文 γ-干扰素释放试验在不明病因类型反复发作葡萄膜炎病因诊断中的临床应用初步研究前言·········································································································9 材料与方法·····························································································10 结果·········································································································13 附图·········································································································15 附表·········································································································17 讨论·········································································································18 结论·········································································································22 参考文献·································································································23 综述结核性葡萄膜炎诊治研究新进展························································26 致谢··················································································································37 个人简历··········································································································38 中中文摘要 PAGE 10万方数据 PAGE 10 万方数据 γ-干扰素释放试验在不明病因类型反复发作葡萄膜炎病因诊断中的临床应用初步研究摘要葡萄膜炎是眼科临床的常见致盲眼病，病因种类繁多，发病机制复杂。因为很多类型葡萄膜炎的发病原因尚未发现，临床病因诊断困难，使治疗难度大大增加，多数葡萄膜炎患者的病情反复发作，造成严重的视力损害，甚至眼球丧失。我国是仅次于印度的全球第二大结核病发病国家，但是报道的结核性葡萄膜炎发病率远远低于国际水平。这主要是由于结核性葡萄膜炎的临床表现形式多种多样，目前尚无特异性的检查方法对其进行明确的诊断。γ-干扰素释放试验（interferon-gamma release assay，IGRA）是近些年来国际上采用的诊断结核病的新方法，其敏感性和特异性都优于结核菌素皮肤试验（tuberculin skin test，TST）。英国国家卫生与临床优化研究所建议对以下两类患者应用 IGRA 检测：一类