局部应用2%盐酸米诺环素软膏治疗慢性牙周炎临床效果观察.docVIP

局部应用2%盐酸米诺环素软膏治疗慢性牙周炎临床效果观察 　　[摘要] 目的 探讨局部应用2%盐酸米诺环素软膏治疗慢性牙周炎的临床效果。 方法 选取本院2011年3月～2013年9月收治的慢性牙周炎患者223例，按照不同治疗方法分为试验组（130例，常规治疗基础上给予局部应用2%盐酸米诺环素软膏）和对照组（93例，常规治疗基础上给予局部应用复方碘甘油），比较两组的治疗效果。 结果 试验组的总有效率（91.54%）明显高于对照组（80.64%）（P0.05）；治疗4周后，试验组GI、PD、TM三项指标的改善情况明显优于对照组（P0.05）。 结论 局部应用2%盐酸米诺环素软膏治疗慢性牙周炎的效果显著，值得临床推广应用。 　　[关键词] 盐酸米诺环素软膏；慢性牙周炎；临床疗效 　　[中图分类号] R781.4+2 [文献标识码] A [文章编号] 1674-4721（2015）02（b）-0061-03 　　Clinical effect observation of 2%minocycline hydrochloride ointment for topical application treating chronic periodontitis 　　CHEN Yue-ying 　　Department of Stomatology，Traditional Chinese Medicine Hospital of Panyu District in Guangzhou City，Guangzhou 511400，China 　　[Abstract] Objective To investigate the clinical effect observation of 2%minocycline hydrochloride ointment for topical application treating chronic periodontitis. Methods 223 patients with chronic periodontitis treated in our hospital from March 2011 to September 2013 were selected，and they were divided into the experimental group （130 cases were given conventional treatment and 2% minocycline hydrochloride ointment for topical application）and control group （93 cases were given conventional treatment and topical application of iodine glycerin），the treatment effect of the two groups was compared. Results The total effective rate of the experimental group （91.54%） was higher than that of control group （80.64%） （P0.05），after 4 weeks treatment，the improvement of GI，PD，TM of the experimental group were better than that of the control group （P0.05）. Conclusion 2% minocycline hydrochloride ointment for topical application treating chronic periodontitis has a significant effect，and it is worthy of clinical promotion and application. 　　[Key words] Minocycline hydrochloride ointment；Chronic periodontitis；Clinical effect 　　牙周炎是一类细菌感染性疾病，堆积在牙颈部及牙龈沟内牙菌斑中的大量微生物是其主要感染源，牙菌斑中致病微生物是牙周炎发生、发展的始动因子，因此采取积极有效的措施清除牙菌斑、防止或减少牙菌斑的再堆积是治疗牙周炎、防止其复发的关键。本研究回顾性分析本院口腔科分别采用2%盐酸米诺环素软膏与常规复方碘甘油局部治疗的共计223例慢性牙周炎患者的临床资料，比较两种治疗方案对慢性牙周炎患