急性阑尾炎患儿C反应蛋白和白细胞计数检测临床意义.docVIP

急性阑尾炎患儿C反应蛋白和白细胞计数检测临床意义 　　【摘要】目的探讨急性阑尾炎患儿检测血清C-反应蛋白(CRP)和白细胞(WBC)计数的临床价值。方法选择急性阑尾炎患儿115例(其中单纯性46例，化脓性38例，坏疽性31例)，分别于手术前及术后第5天采血进行血清CRP和WBC计数检测，并与33例健康儿童的血清CRP和WBC计数进行对照分析。结果急性阑尾炎单纯性组、化脓性组和坏疽性组血清CRP水平和WBC计数比较均有极显著性差异(单纯性组化脓性组坏疽性组，P均0.01)，且均显著高于对照组(P0.01)；3组术后CRP水平和WBC计数均较术前显著降低(P0.01)，但仍然高于对照组(P0.01)。有并发症组血清CRP水平和WBC计数较无并发症组显著升高(P0.01)。 结论急性阑尾炎患儿检测血清CRP和WBC计数对判断病情及预后有重要价值。 　　【关键词】小儿；急性阑尾炎；C-反应蛋白；白细胞 　　 　　Detection of C-reactive protein and white blood cell count in children with acute appendicitis and their significanceWEI De-cai, JIANG Bang-hao, ZHOU Si-dong, et al.Department of Surgery, Zhongcun Hospital of Panyu District in Guangzhou, Guangzhou 511495,China 　　【Abstract】ObjectiveTo explore the clinical significance of serum C-reactive protein (CRP) and white blood cell(WBC)count detected in children with acute appendicitis. MethodsThe level of serum CRP and WBC count of 115 children with acute appendicitis(pathologic type 46 cases of simple acute appendicitis, 38 cases of pyogenic acute appendicitis, and 31 cases of gangrenous acute appendicitis) before operation and 5th day post-operation, and those of 33 healthy children (the control) were detected and analyzed. ResultsThere were significantly differences among the sub-groups of acute appendicitis of the level of CRP and WBC count (simple acute appendicitis grouppyogenic acute appendicitis groupgangrenous acute appendicitis group, all P0.01), and higher than that of the control(all P0.01). Compared with before operation, the serum level of CRP and WBC count in acute appendicitis children decreased significantly after operation(P0.01), but still higher than that of the control(P0.01). The level of CRP and WBC count of group with complication after operation were higher than those of group without complication(P0.01). ConclusionThe detection of serum CRP and WBC count has important value for prediction of the severity and prognosis of children with acute appendicitis. 　　【Key words】Children; Acute appendicit