CT引导下经皮射频消融术治疗骶骨骨样骨瘤.DOC

CT-guided percutaneous radiofrequency ablation of spinal osteoid osteoma LIU Chen, HAN Song-bo, Department of Radiology, Peking University Third Hospital, Beijing 100191, China(Liu C, Han SB, Ma YQ) Department of HYPERLINK app:ds:orthopedicsOrthopedics, Peking University Third Hospital, Beijing 100191, China(Liu XG, Zhu B) Correspondence to: Dr.YUAN Hui-shu, 100191, Tel: 86-10 Email: huishuy@ Keywords: spinal tumor; osteoid osteoma; CT-guided; radiofrequency ablation; minimally invasive Background This study evaluated the feasibility, efficacy and safety of CT-guided percutaneous radiofrequency ablation in patients with spinal osteoid osteoma. Methods Two patients suffered spinal osteoid osteoma were treated with CT-guided percutaneous radiofrequency ablation under local anesthesia. Lesions located in sacral vertebrae and cervical vertebrae, which were adjacent to nerve root and spinal canal respectively. Tumors were treated under 90℃ radiofrequency temperature lasting 4 minutes by an electrode placement. Visual analog scale was used to evaluate the pain improvement. Results No complications ware observed pre- and post-operation. Patients recovered to normal activities immediately and achieved complete pain relief in 24 hours. No symptoms were recurrent in 5 months and 4 months follow up. Mild scoliosis has been recovered in case 2. Conclusions CT-guided percutaneous radiofrequency ablation of spinal osteoid osteoma is safe, effective and has more clinical benefits. The long-term outcome needs further observation. Osteoid osteoma (OO) was first reported by Jaffe in 19351, accounted for 10% of all benign bone tumors2, which is most common for teenagers. The major symptoms are manifested with severe pain, scoliosis and neurologic deficit. OO cound occur in any bone, especially common in tibia and femur, less involving the spine. Traditional treatments are nonsteroidal anti-inflammatory drugs (NSAIDs) and surgical resection. NSAIDs are effective but achieve