探讨氯吡格雷联合复方丹参滴丸治疗老年冠心病疗效及作用机制.docVIP

探讨氯吡格雷联合复方丹参滴丸治疗老年冠心病疗效及作用机制 　　[摘要] 目的 探讨氯吡格雷联合复方丹参滴丸治疗老年冠心病的疗效及作用机制。 方法 方便选取2013年11月―2015年11月住院治疗的132例老年冠心病患者作为探讨对象，根据药物治疗方式的不同将其分为研究组和对照组，研究组患者采取氯吡格雷联合复方丹参滴丸治疗，对照组患者采用阿托伐他汀钙治疗，并比较两组患者临床治疗效果以及治疗后生活指标和心电图改善情况。结果 研究组患者临床治疗总有效率和心电图有效率分别为94.7%和97.4，对照组患者分别为，83.9%和87.5%，两组比较差异具有统计学意义（P0.05）；研究组患者血栓素B2、PS、IL-6和CRP血清含量均明显少于对照组（P0.05）。 结论 复发丹参滴丸联合氯吡咯雷在治疗冠心病患者方面临床效果较好，具有抗氧和抗血小板聚集的作用，能有效减少血脂水平和改善患者临床症状。 　　[关键词] 复发丹参滴丸；氯吡咯雷；老年冠心病；临床效果；作用机制 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2016）08（c）-0142-03 　　Discussion Clopidogrel CSDP Treatment of Elderly Patients with Coronary Heart Disease Effect and Mechanism 　　WANG Cheng-jun， ZHANG Yue-yuan 　　Cardiology， Chinese Peoples Liberation Army 71887 Army Hospital， Penglai， Shandong Province，265600 China 　　[Abstract] Objective Discussion clopidogrel CSDP treatment of elderly patients with coronary heart disease effect and mechanism. Methods Convenient selection select November 2013―November 2015 132 hospitalized elderly patients with coronary heart disease as explore objects， depending on the drug treatment will be divided into study group and control group， the study group of patients taking clopidogrel plus Danshen drop pill treatment， the control group were treated with atorvastatin calcium therapy， and compared two groups of patients after treatment， clinical treatment and living index and electrocardiogram improve the situation. Results Clinical treatment of patients total effective rate and ECG effective rate was 94.7% and 97.4， respectively， of patients in the control group， 83.9% and 87.5%， the difference was statistically significant （P 0.05）； The study group patients thromboxane B2， PS， IL-6 and CRP serum levels were significantly less than the control group （P 0.05）.Conclusion Salvia Dropping Pill Combined relapse clopidogrel in the treatment of coronary heart disease patients better clinical aspects， has antioxidant and anti-platelet aggregation effect， can effectively reduce blood lipid levels and improve clinical sym