氯吡格雷联合氟伐他汀治疗脑梗死临床疗效观察.docVIP

氯吡格雷联合氟伐他汀治疗脑梗死临床疗效观察 　　【摘要】 目的：探讨氯吡格雷联合氟伐他汀治疗脑梗死的临床疗效。方法：选择本院2012年3月-2014年3月收治的84例脑梗死患者为研究对象，随机分为对照组和观察组，每组各42例。对照组行常规治疗，观察组行氯吡格雷联合氟伐他汀治疗，对两组患者临床治疗效果进行分析。结果：观察组治疗总有效率为92.86%，对照组为71.43%，差异有统计学意义（P0.05），经治疗后，观察组显著优于对照组，差异有统计学意义（P0.05）；两组患者的ADL评分及NIHSS评分对比显示，治疗前无明显差异，但是经治疗后，两组患者均有明显变化，且观察组显著优于对照组，差异有统计学意义（P0.05）。结论：采取氯吡格雷联合氟伐他汀治疗脑梗死，安全性高，可有效修复脑神经损伤，提高患者日常生活能力，改善血脂水平，利于患者恢复，值得临床进一步推广使用。 　　【关键词】 氯吡格雷； 氟伐他汀； 脑梗死 　　The Clinical Effect Observation of Cerebral Infarction in Treatment of Clopidogrel Combining with Fluvastatin/LIANG Guo-hua，LAI Bao-yu，SU Chi，et al.//Medical Innovation of China，2015，12（08）：036-038 　　【Abstract】 Objective： To probe the clinical effect observation of cerebral infarction in treatment of clopidogrel combining with fluvastatin.Method：84 patients who suffered from cerebral infarction and accepted treatment in our hospital were selected as the research objects from March 2012 to March 2014，and these patients were randomly divided into the control group，and observation group，42 patients in each group. In the control group， they were treated with the routine curing while in the observation group， they were treated with the method of clopidogrel combining with fluvastatin.Then， the clinical effects of both groups were analyzed.Result：The overall effective rate of treatment in the observation group was 92.86%， compared that of 71.43% in the control group，the difference was statistically significance（P0.05）. However， after the treatment， the observation group was evidently better than the control group，the differences had the statistically significance（P0.05）.Furthermore， according to the ADL score and the NIHSS score of these two groups， before the treatment， they had no evident differences. However， after the treatment， both these two groups of patients had evident differences and the observation group was evidently better than the control group， the difference was statistically significant（P0.05）.Conclusion：The treatment of cerebral infarction with