氨溴索注射液异丙托溴铵布地奈德混悬液联合治疗小儿支气管肺炎临床观察.docVIP

氨溴索注射液异丙托溴铵布地奈德混悬液联合治疗小儿支气管肺炎临床观察 　　摘要：目的 研究氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗小儿支气管肺炎的临床疗效。方法 选取2014年1月～2016年12月于我院就诊的支气管肺炎患儿98例，采用随机数字表法，均分为观察组与对照组各49例，对照组患儿给予常规治疗，观察组患儿在此基础上给予氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗，对比两组患儿的治疗效果。结果 观察组患儿的治疗总有效率显著高于对照组（P0.05）；观察组患儿的发热、气促、憋喘、咳嗽、肺部X射线消失/缓解/恢复时间均显著短于对照组（P0.05）；观察组患儿治疗后的CRP、IL-6、TNF-α、WBC均显著低于对照组（P0.05）。结论 氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗能够有效改善支气管肺炎患儿的临床症状，临床疗效显著，具有推广使用价值。 　　关键词：小儿支气管肺炎；氨溴索注射液；异丙托溴铵；布地奈德混悬液 　　中图分类号：R725.6 文献标识码：A 文章编号：1006-1959（2017）24-0079-03 　　Clinical Observation of Combination of Ambroxol Injection，Ipratropium Bromide and Budesonide Suspension in Children with Bronchial Pneumonia 　　WU Yun-duo，LIN Xiao-fei，HUA Wei 　　（Department of Pediatrics，Huaian Maternal and Child Health Hospital，Huaian 223000，Jiangsu，China） 　　Abstract：Objective To study the clinical efficacy of ambroxol injection，ipratropium bromide，budesonide suspension combined with aerosol inhalation in children with bronchial pneumonia.Methods 98 cases of bronchial pneumonia from January 2014～2016 year in December in our hospital，were randomly divided into observation group and control group with 49 cases in each group，the control group were given conventional treatment， observation group were given ambroxol hydrochloride injection，ipratropium bromide and Budesonide aerosol inhalation treatment of the two groups were compared.Results The therapeutic effect of treatment in the observation group the total effective rate was significantly higher than that of the control group（P0.05）；observation group of children with fever，shortness of breath，dyspnea，cough，lung X ray disappeared/response/recovery time were significantly shorter than the control group（P0.05）；the treatment in the observation group after CRP，IL-6，TNF-α，WBC were significantly lower than the control group（P0.05）.Conclusion Ambroxol，ipratropium bromide and budesonide inhalation therapy can effectively improve the clinical symptoms in children with bronchial pneumonia，the clinical curative effect is