氟哌噻吨美利曲辛联合心理干预在慢性阻塞性肺疾病伴焦虑抑郁患者中应用效果.docVIP

氟哌噻吨美利曲辛联合心理干预在慢性阻塞性肺疾病伴焦虑抑郁患者中应用效果 　　[摘要] 目的 ?^察氟哌噻吨美利曲辛联合心理干预在慢性阻塞性肺疾病（COPD）伴焦虑抑郁患者中的应用效果。 方法 选择第三军医大学新桥医院2015年1月～2016年10月收治的COPD伴焦虑抑郁患者76例按随机数字表法分为对照组和观察组，每组各38例。对照组患者给予常规抗炎、解痉、平喘、控制性氧疗、祛痰及对症支持治疗。观察组在对照组治疗的基础上加用氟哌噻吨美利曲辛，并给予心理干预。两组均以2周为1个疗程。观察两组临床疗效，比较两组患者治疗前后汉密尔顿焦虑量表（HAMA）和汉密尔顿抑郁量表（HAMD）评分，以及COPD评估测试（CAT）结果。 结果 观察组患者总有效率显著高于对照组，差异有统计学意义（P 0.05），观察组治疗后CAT评分较治疗前显著降低，且显著低于对照组，差异均有统计学意义（P 0.05）。 结论 氟哌噻吨美利曲辛联合心理干预对COPD伴焦虑抑郁患者的临床疗效确切，其不仅能改善患者临床症状和焦虑抑郁状态，还能明显提高患者的生活质量。 　　[关键词] 氟哌噻吨美利曲辛；心理干预；慢性阻塞性肺疾病；焦虑抑郁 　　[中图分类号] R563.9；R749.4 [文献标识码] A [文章编号] 1673-7210（2017）05（a）-0065-04 　　Application effect of Flupenthixol Melitracen combined with psychological intervention in chronic obstructive pulmonary disease patients with anxiety-depression 　　1.Department of Neurology， Xinqiao Hospital， Third Military Medical University， Chongqing 400037， China； 2.Department of Internal Medicine， Gaoxin Peoples Hospital of Chongqing City， Chongqing 400039， China 　　[Abstract] Objective To observe the application effect of Flupenthixol Melitracen combined with psychological intervention in chronic obstructive pulmonary disease （COPD） patients with anxiety-depression. Methods From January 2015 to October 2016， in Xinqiao Hospital， Third Military Medical University， 76 COPD patients with anxiety-depression were selected， they were divided into control group and observation group by random number table， with 38 cases in each group. The control group was given conventional anti-inflammation， spasmolysis， relieving asthma， controlled oxygen therapy， eliminating phlegm and symptomatic and supportive treatment. On basis of control group， the observation group was added with Flupenthixol Melitracen and psychological intervention. Both groups were taken 2 weeks as a course. The clinical effects of the two groups were observed， the scores of Hamilton anxiety scale （HAMA） and Hamilton depression scale （HAMD）， and the scores of chronic obstructive pulmonary disease assessment test （CAT） of the two g