甘精胰岛素联合二甲双胍治疗初发2型糖尿病伴肥胖症临床研究.docVIP

甘精胰岛素联合二甲双胍治疗初发2型糖尿病伴肥胖症临床研究 　　[摘要] 目的 分析治疗初发2型糖尿病伴肥胖症采用甘精胰岛素联合二甲双胍方式的临床疗效。方法 随机选取2016年3月―2017年1月该院收治的60例初发2型糖尿病伴肥胖症患者资料，分为观察组与参照组，予以参照组患者甘精胰岛素治疗，予以观察组患者甘精胰岛素联合二甲双胍治疗，观察并对比两组患者的临床疗效。结果 通过治疗，两组患者的血糖水平均得到明显控制，但参照组的控制效果要低于观察组，差异有统计学意义（P0.05）；另外，观察组患者的胰岛素日用量、血糖达标时间、体重指数值均显著低于参照组差异有计学意义（P0.05）。 结论 初发2型糖尿病伴肥胖症患者采用甘精胰岛素联合二甲双胍治疗方式，可改善临床症状，提高生活质量，值得推广。 　　[关键词] 初发2型糖尿病伴肥胖症；二甲双弧；甘精胰岛素 　　[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062（2017）07（b）-0019-02 　　Clinical Research on Insulin Glargine and Melbine in Treatment of Newly-diagnosed Type 2 Diabetes and Obesity 　　HAN Xing-min 　　Department of Pharmacy， Zibo Traditional Chinese and Western Medicine Hospital， Zibo， Shandong Province， 255026 China 　　[Abstract] Objective To analyze the curative effect of insulin glargine and melbine in treatment of newly-diagnosed type 2 diabetes and obesity. Methods 60 cases of patients with newly-diagnosed type 2 diabetes and obesity admitted and treated in our hospital from March 2016 to January 2017 were randomly selected and divided into two groups， the control group were treated with insulin glargine， while the observation group were treated with insulin glargine and melbine， and the clinical curative effect was compared between the two groups. Results After treatment， the blood glucose level of the two groups was obviously controlled， and the control effect in the control group was lower than that in the observation group， and the difference between groups was statistically significant（P0.05）， besides， the daily dose of insulin， blood glucose standards time and weight index value in the observation group were obviously lower than those in the control group， and the differences were obvious with statistical significance（P0.05）. Conclusion The insulin glargine and melbine in treatment of newly-diagnosed type 2 diabetes and obesity can improve the clinical symptoms and improve the quality of life， and it is worth promotion. 　　[Key words] Newly-diagnosed type 2 diabetes and obesity； Melbine； I