癫痫持续状态相关因素临床研究.docVIP

癫痫持续状态相关因素临床研究 　　【摘 要】 目的 探讨癫痫持续状态发病的相关危险因素，为癫痫持续状态的治疗提供参考。方法 回顾性分析2013年1月至2015年1月滨州医学院附属医院神经内科住院治疗的癫痫持续状态患者，共纳入72例，收集患者的临床资料。对所有患者进行随访，采用格拉斯哥预后评分评价患者预后情况，分析与预后相关的危险因素。结果 患者男女性别之比为4.54：1，男性发病率显著高于女性（X2=43.581，P0.01）；儿童占29.17%，成人占70.83%，成人的发病率显著高于儿童（X2=42.335，P0.01）；CSE63例，NCSE9例，CSE的发病率显著高于NCSE，差异有统计学意义（X2=46.611，P0.01）；颅脑损伤、病毒性脑炎急性期和脑血管病变是癫痫持续状态发病的危险因素。结论 癫痫持续状态在各年龄段均可见，成人发病率高于儿童，男性高于女性，颅脑损伤、病毒性脑炎急性期和脑血管病变是癫痫持续状态发病的危险因素。 　　【关键词】 癫痫持续状态 危险因素 临床特点 预后 　　Clinical study status epilepticus related factors 　　Fu Haihong1，2， Fan Weiming1 　　1：Department of neurology， affiliated hospital of Binzhou Medical University， Binzhou 256603， China 　　2：Dongming People’s Hospital Dongming 274500， China 　　【Abstract】 Objective To investigate the status epilepticus associated risk factors， provide a reference for the treatment of status epilepticus. Methods A retrospective analysis of epilepsy from January 2013 to January 2015， Affiliated Hospital of Binzhou Medical College， Department of Neurology， continued state of patients hospitalized， 72 cases were included collecting clinical data. All patients were followed up， using the Glasgow Outcome Scale evaluate the prognosis of patients and to analyze the risk factors associated with prognosis. Results Patients gender ratio of 4.54： 1， male incidence was significantly higher than women （X2 = 43.581， P 0.01）； children account for 29.17%， accounting for 70.83 percent of adult incidence was significantly higher than adult children （X2= 42.335 ， P 0.01）； CSE63 cases， NCSE9 example， CSE incidence was significantly higher than NCSE， the difference was statistically significant （X2= 46.611， P 0.01）； traumatic brain injury， acute phase of viral encephalitis and cerebral vascular disease It is a risk factor for the onset of status epilepticus. Conclusion Status epilepticus are visible at all ages， adult incidence in children， in men than women， traumatic brain injury， acute phase of viral encephalitis and cerebral vascular disease are risk f