糖尿病对慢性阻塞性肺疾病患者肺功能影响相关性研究.docVIP

糖尿病对慢性阻塞性肺疾病患者肺功能影响相关性研究 　　[摘要] 目的 观察糖尿病对于慢性阻塞性肺疾病（COPD）患者肺功能及血气分析情况的影响。 方法 回顾性分析2015年1月―2016年12月间在该院诊治的慢性阻塞性肺疾病（COPD）患者80例，根据有无合并糖尿病，分为试验组及对照组， 通过肺功能检测及血气分析，测量VC、FVC、FEV1、FEV1/FVC、PEF 、??散量DLCO与比弥散量DLCO/PRED等肺功能指标，并进行组间比较，分析严重程度之间的差异。 结果 试验组肺功能指标显著低于对照组。试验组的疾病严重程度也高于对照组患者，差异有统计学意义（P0.05）。结论 慢性阻塞性肺疾病（COPD） 患者合并糖尿病时，其的肺功能受损情况更严重，COPD合并糖尿病时肺通气功能和弥散功能都可受损。 　　[关键词] COPD；糖尿病；肺功能 　　[中图分类号] R563 [文献标识码] A [文章编号] 1672-4062（2017）02（b）-0141-02 　　Related Research on Effect of Diabetes on the Lung Function of Patients with Chronic Obstructive Pulmonary Diseases 　　MA Hai-lan 　　Outpatient Department， Hegang People’s Hospital， Hegang， Heilongjiang Province， 154101 China 　　[Abstract] Objective To observe the effect of diabetes on the lung function and blood gas analysis of patients with chronic obstructive pulmonary diseases. Methods 80 cases of patients with chronic obstructive pulmonary diseases treated in our hospital from January 2015 to December 2016 were retrospectively analyzed and divided into two groups according to whether the patients were with diabetes or not， and the lung function indexes such as VC， FVC， FEV1， FEV1/FVC， PEF， diffusing capacity DLCO and diffusing capacity DLCO/PRED were compared by the lung function test and blood gas analysis， and the difference in the severity was analyzed. Results The lung function indexes in the test group were obviously lower than those in the control group， and the disease severity in the test group was higher than that in the control group， and the difference was statistically significant（P0.05）. Conclusion The lung function injury of patients with COPD and diabetes is more severe， and the pulmonary ventilation function and diffusing function may be injured for patients with COPD and diabetes. 　　[Key words] COPD； Diabetes； Lung function 　　慢性阻塞性肺疾病（chronic obstructive pulmona-ry disease，COPD）的疾病特点为气流受限不完全可逆，呈进行性发展。同时伴随着病程发生、进展，患者肺功能呈进行性减退，是严重影响患者生活质量及其劳动力的一种疾病[1]， 在中国是一种常见的疾病，患病率为8.2%（95%CI，7.9～8.6）[2]。慢性阻塞性肺疾病的危害因素已被广泛