药物流产后雌孕激素序贯疗法临床对比研究.docVIP

药物流产后雌孕激素序贯疗法临床对比研究 　　[摘要] 目的：探讨在药物流产后使用雌孕激素对缩短阴道出血时间及减少清宫的作用。方法：将早孕行药物流产者随机分为观察组和对照组各52例。观察组从胎囊排出的第5天开始每天服用雌激素戊酸雌二醇片1 mg 21 d，后10 d加用安宫黄体酮4 mg。观察两组阴道出血时间、子宫内膜修复和宫内残留情况。结果：观察组药物流产后阴道出血时间，明显短于对照组（t=5.802，P＜0.05）。药物流产15 d后B超检查，观察组中55.77%（29/52）有内膜修复，而对照组只有17.31%（9/52）修复，差异有统计学意义（P＜0.05）。两组转经情况没有异常差异。观察组无需要清宫者，而对照组1例，没有明显差异性。结论：药物流产胎囊排出后加用雌孕激素，可促进子宫内膜修复，缩短阴道出血时间，减少清宫情况的发生。 　　[关键词] 药物流产；雌孕激素；流血；清宫 　　[中图分类号] R714.21 [文献标识码]A[文章编号]1674-4721（2011）03（c）-049-02 　　 　　Clinical comparison of estrogen-progesterone sequential therapy after drug drug abortion 　　ZHANG Lin 　　The Coal Spa, Linyi City, Shandong Province, Linyi 276032, China 　　[Abstract] Objective: To investigate the use of medical abortion reduced estrogen and progesterone vaginal bleeding and reduce the role of curettage. Methods: The medical abortion of early pregnancy were randomly divided into two groups and the control group of 52 cases. Discharged from the fetal sac observation group on day 5 daily doses of estrogen estradiol valerate tablets 1 mg 21 d, 10 d after the addition of medroxyprogesterone acetate 4 mg. Time were observed vaginal bleeding and endometrial repair and intrauterine residual. Results: Vaginal bleeding after medical abortion group significantly shorter than the control group (t=5.802, P0.05). After 15 days after medical abortion ultrasound B, 55.77% in the observation group (29/52) with endometrial repair, while the control group only 17.31% (9/52) fix, the difference was statistically significant (P0.05). Two sets of turning the situation was not unusual differences. There was no need for curettage were observed in the control group 1 patients, no significant difference. Conclusion: Medical abortion after fetal sac discharge plus estrogen and progesterone can promote endometrial repair, shorten the bleeding time, reduce currettage happen. 　　[Key words] Medical abortion; Estrogen and progesterone; Bleeding; Currettage 　　 　　米非司酮配伍米索前列醇终止早孕这一非创伤性治疗方案越来越被广大早孕患者所接受。但它所带来的不全流产、药物流产后出血