舒芬太尼与瑞芬太尼在急诊脑外伤手术麻醉中应用效果观察及安全性评价.docVIP

舒芬太尼与瑞芬太尼在急诊脑外伤手术麻醉中应用效果观察及安全性评价 　　[摘要]目的 研究舒芬太尼与瑞芬太尼在急诊脑外伤手术麻醉中的应用效果以及安全性。方法 以麻醉方式为背景，随机选择2013年1月―2014年10月急诊科收入治疗的80例脑外伤患者作为研究对象，所有患者均接受手术治疗，行舒芬太尼麻醉的40例患者作为研究组，行瑞芬太尼麻醉的40例患者作为对照组，归纳分析两种麻醉方式的临床效果及安全性。结果 研究组不良反应发生率为7.5%，对照组为12.5%，组间差异无统计学意义（P0.05）；两组患者在CM-RO2、CBF、ICP、心率、平均动脉压、恢复自主呼吸时间以及睁眼时间的比较上，差异有统计学意义（P0.05）。结论 舒芬太尼在临床急诊脑外伤手术患者的麻醉中效果优于瑞芬太尼，血流动力学指标及颅脑功能稳定，有效降低患者术后苏醒时间，可作为安全可靠的麻醉方式在外科手术中进行推广。 　　[关键词]舒芬太尼；瑞芬太尼；急诊脑外伤；麻醉效果；安全性 　　[中图分类号]R59 [文献标识码]A [文章编号]1674-0742（2015）03（c）-0139-02 　　[Abstract]Objective This paper is to investigate application effects of Sufentanil and Remifentanil in emergency brain trauma surgical anesthesia and the safety.Methods Eighty patients with brain trauma in December， 2013 to December， 2014 admitted and treatment by the Emergency Department with the anesthesia as background were selected as research subjects， all patients were treated with surgeries， 40 patients undergoing Sufentanil anesthesia were divided into the research group， and remaining 40 patients undergoing Remifentanil anesthesia were divided into the control group， clinical efficacy and safety of anesthesia methods were inductively analyzed.Results The incidence of adverse reactions in the research group hit 7.5%， and that value in the control group hit 12.5%， and there were not significant differences between groups（P0.05）. The comparisons in CM - RO2，CBF，ICP，heart rate， mean arterial pressure， and recovery time of spontaneous breathing and the time of opening（P0.05）， the differences were statistically significant.Conclusions The anesthesia effect of Sufentanil in clinical emergency treatment of patients undergoing brain trauma surgeries was better than that of Remifentanil， hemodynamic index and cerebral function are stability， effectively reducing awakening time of postoperative patients， and it can be promoted as a safe and reliable way of anesthesia. 　　[Key words] Sufentanil；Remifentanil；Emergency Brain Trauma；Anesthesia Effect；Safety 　　临床神经外科麻醉研究内容包含术前用药、麻醉诱导、气管内插管、