肺结核合并糖尿病患者营养状态影响因素分析.docVIP

肺结核合并糖尿病患者营养状态影响因素分析 　　[摘要] 目的 探讨影响肺结核（PTB）合并糖尿病（DM）患者营养状态不良的危险因素。 方法 回顾性分析我院60例PTB-DM患者临床资料，根据治疗后6个月患者的营养状态将其分为营养状态良好组（n=37）和营养状态不良组（n=23）。将两组临床资料做统计学分析处理，利用多因素Logistic回归分析法分析影响PTB-DM患者预后营养状态不良的高危因素。 结果 两组性别和出院后吸烟情况比较差异无统计学意义（P0.05）；经多因素Logistic回归分析发现，年龄、入院时出现病灶空洞情况、出院后饮酒与DM控制情况均为影响PTB-DM患者预后营养状态不良的独立危险因素（P0.05）。 结论 年龄较大、入院时存在病灶空洞、出院后存在饮酒和DM控制较差情况均与PTB-DM患者预后营养状态不良关系密切，需引起重视。 　　[关键词] 肺结核；糖尿病；营养状况；危险因素 　　[中图分类号] R587.1 [文献标识码] A [文章编号] 1673-9701（2018）02-0020-03 　　[Abstract] Objective To explore the risk factors of malnutrition in the patients with pulmonary tuberculosis （PTB） complicated with diabetes mellitus （DM）. Methods The clinical data of 60 patients with PTB-DM in our hospital were retrospectively analyzed. According to the nutritional status of patients after 6 months of treatment， they were divided into favorable nutrition group（n=37） and malnutrition group （n=23）. The clinical data of the two groups were analyzed statistically. Multivariate Logistic regression analysis was used to analyze the risk factors of malnutrition prognosis in PTB-DM patients. Results There was no statistically significant difference in gender and smoking after discharge between the two groups（P0.05）； multivariate Logistic regression analysis showed that age， incidence of cavitary lesion upon admission and drinking and DM control after discharge were all dependent risk factors of malnutrition prognosis in PTB-DM patients（P0.05）. Conclusion Advanced age， cavitary lesion upon admission， drinking and poor DM control after discharge are closely related to the malnutrition prognosis in PTB-DM patients， and great attention should be drawn to them. 　　[Key words] Pulmonary tuberculosis； Diabetes mellitus； Nutritional status； Risk factors 　　我国糖尿病（DM）与肺结核（PTB）发病率均较高，而DM的病理生理学特征使患者身体素质降低而增加PTB发生风险，也影响PTB患者的治疗效果，故PTB-DM患者的预后状态受到学术界广泛关注[1]。PTB-DM患者治疗后机体调节功能尚未完全恢复，常使患者营养状态处于较差水平，严重影响患者的预后状态，也增加疾病复发风险。基于此，本研究对PTB-DM患者临床资料进行回?性分析，试图发现影响PTB-DM患者营养状态不良的危险因素，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　回顾性