舒利迭气雾剂及氟替卡松气雾剂联合孟鲁司特钠口服治疗哮喘临床效果分析.docVIP

舒利迭气雾剂及氟替卡松气雾剂联合孟鲁司特钠口服治疗哮喘临床效果分析 　　[摘要] 目的 对比在治疗哮喘中应用舒利迭气雾剂吸入以及氟替卡松气雾剂吸入与孟鲁司特钠联合治疗的临床效果。方法 将本院从2016年4月～2017年4月期间收治的62例哮喘患者作为研究样本，以随机数字表法将其均分为观察组与对照组，每组各31例，将采取舒利迭气雾剂吸入治疗患者作为观察组，将采取氟替卡松气雾剂吸入与孟鲁司特钠联合治疗患者作为对照组，分析对比两组哮喘患者经不同干预理后的临床治疗效果。 结果 观察组哮喘患者组胺水平与对照组对比差异无统计学意义（P0.05）。观察组哮喘患者不良反应发生率、C-LT水平、IL-8水平、FEV1、夜间PEF、白天PEF与对照组对比差异有统计学意义（P0.05）。 结论 将舒利迭气雾剂吸入以及氟替卡松气雾剂吸入与孟鲁司特钠联合治疗应用在哮喘临床治疗中均可获得显著效果，舒利迭气雾剂吸入更具应用的优势。 　　[关键词] 舒利迭气雾剂吸入；氟替卡松气雾剂吸入；孟鲁司特钠；哮喘 　　[中图分类号] R562.25 [文献标识码] B [文章编号] 1673-9701（2017）35-0108-03 　　[Abstract] Objective To compare the clinical effects of the combination of seretide aerosol inhalation and fluticasone aerosol inhalation with montelukast in the treatment of asthma. Methods 62 asthmatic patients admitted from April 2016 to April 2017 in our hospital were selected as the research samples. The patients were divided equally into the observation group and the control group by random number table， with 31 cases in each group. Patients who were treated with seretide aerosol inhalation were selected as observation group. The patients who were given seretide aerosol inhalation combined with montelukast were chosen as the ontrol group. The clinical treatment effects between the two groups of patients with asthma after different interventions were analyzed and compared. Results There was no significant difference between the observation group and the control group in the histamine level（P0.05）. The incidence of adverse reactions， C-LT level， IL-8 level， FEV1， nighttime PEF and daytime PEF in the observation group were significantly different from those in the control group（P0.05）. Conclusion The combination of seretide aerosol inhalation and fluticasone aerosol inhalation with montelukast both can achieve significant effect in the clinical treatment of asthma. The use of seretide aerosol inhalation has more application advantages. 　　[Key words] Seretide aerosol inhalation； Fluticasone aerosol inhalation； Montelukast； Asthma 　　哮喘是因气道结构细胞、炎性细胞、细胞组胺等多种细胞参与引发