胃肠外营养治疗危重症新生儿疗效观察.docVIP

胃肠外营养治疗危重症新生儿疗效观察 　　【摘要】目的观察使用全胃肠外营养(TPN)治疗危重症新生儿的疗效。方法将114例危重症新生儿分成两组，治疗组60例，使用TPN的时间均≥7天，对照组54例，未使用TPN。两组治疗前后检查监测患儿体重、头围、身长，治疗10天后比较疗效。结果治疗组平均体重、头围、身长日增量均优于对照组，两组间的差别有显著性意义(??P??0.01或0.05)，两组疗效的比较经Ridit分析，治疗组的疗效优于对照组(??P??0.01)。结论胃肠外营养可明显增加高危新生儿的体重，提高高危新生儿的抢救成功率。 　　?ぁ竟丶?词】胃肠外营养；危重新生儿；NICU?? 　　文章编号：1003-1383(2006)03-0239-02 　　中图分类号：R 722.6文献标识码：A?? 　　 　　The treatment of TPN on high risk Newborn in NICU 　　LIU Dong，LIU Chen??zhou，LI Hong??mei，QI Yue，CHEN Li??mei?? 　　(Department of Pediatrics, Jiangmen Central Hospital, JiangmenGuangdong ,529070) ?お? 　　 　　【Abstract】ObjectiveTo analyze the effects of TPN on treating high??risk newborns in NICU. 　　Methods114 cases of high??risk newborns in NICU were randomly divided into two groups: 60 cases in the experimental group and 54 cases in the control group. The experimental group used TPN at least 7days, while the control group did not use it. All cases had their body??weight examined after 10 days of treatment. The results were observed and analyzed.ResultsIn experimental group, the weight of body increased by an average of20.17±3.36 g per day, while in the control group the body??weight added 12.09±1.87 g averages per day. There were extreme differences between two groups (??P??0.01). The results in the experimental group are much better than those in the control group (??P??0.01). Con 　　clusionTPN can obviously raise the body??weight and the successful salvage rate of high??risk newborns in NICU. 　　?ぁ?Key words】TPN；high??risk newborn；NICU?? 　　 　　自1968年Dudrick首次报道全胃肠外营养液(TPN)应用于临床后[1]，现已广泛应用于临床各个专业。国内外众多的研究和临床实践证明，胃肠道外营养的临床应用对提高危重病儿的抢救成功率，提高成活率及生存质量等方面都有显著的作用。现将我院NICU 2002年1月～2005年10月期间收治的危重新生儿，对其使用TPN的临床疗效报道如下。 　　 　　?ぷ柿虾头椒? 　　 　　1.一般资料以我院NICU收治的60例危重症新生儿(包括早产儿、极低体重儿、超低体重儿)为治疗组，对照组为同期54例因经济原因未采用TPN的新生儿，两组治疗前的一般情况(性别比、日龄、胎龄、阿氏评分)以及两组患儿治疗前观察指标(头围、体重、身长)无显著差异(??P??0.05)。两组患儿的疾病类别为：单纯早产生活力低下15例，颅脑疾患(窒息、缺血缺氧性脑病、颅内出血、感染等)18例，消化道疾患(坏死性小肠结肠炎、畸形、出血、胃食道反流等)15例，伴有单和/或多器官功能衰竭(心血管、呼吸、脑、消化道、DIC)37例，新生儿肺透明膜病14例，新生儿破伤风3