视网膜中央动脉阻塞患者凝血功能分析.docVIP

视网膜中央动脉阻塞患者凝血功能分析 　　摘要：目的 分析视网膜中央动脉阻塞（central retinal artery occlusion，CRAO）患者的凝血功能情况，推测血栓形成是否是CRAO发病的主要危险因素。方法 回顾性研究将CRAO患者作为病变组，与之年龄、性别相匹配的普通人群作为对照组，进行凝血功能检查，将统计结果进行t检验，评价凝血功能差异是否有统计学意义及临床意义。结果 60例病变组与60例对照组凝血功能进行比较：49例男性病变组与49例男性对照组凝血功能进行比较，PT活动度、国际标准化比值、纤维蛋白原三项检查，差异具有统计学意义（P0.05），却无临床意义。11例女性病变组和11例女性对照组凝血功能检查，PT活动度和纤维蛋白原两项，差异具有统计学意义（P0.05），却无临床意义。结论 CRAO患者与普通人群相比，凝血功能检查结果差异无临床意义。CRAO患者无明显血栓形成倾向，进一步推测血栓形成不是CRAO的主要病因。 　　关键词：视网膜中央动脉阻塞；危险因素；凝血功能；凝血酶原时间；活化部分凝血活酶时间 　　Abstract：Objective To analyze the central retinal artery occlusion（central retinal artery occlusion，CRAO）the blood coagulation function of patients， whether that thrombosis is a major risk factor for the onset of CRAO.Methods A retrospective study of CRAO patients as the disease group，with age and sex matched normal people as control group，coagulation function examination，statistics the results of t test，the difference of coagulation function and clinical significance of evaluation of whether there is statistical significance.Results 60 cases of disease group and 60 cases of control group were compared with blood coagulation function：49 cases of male disease group and 49 cases of male control group blood coagulation function were compared，PT activity，international normalized ratio，fibrinogen three check，the difference was statistically significant（P0.05），but no clinical significance.11 cases of female disease group and 11 cases of female control group coagulation tests，PT activity and fibrinogen of two，the difference was statistically significant（P0.05），but no clinical significance.Conclusion The CRAO patients compared with the general population，coagulation function test results showed no clinical significance.CRAO patients had no tendency to thrombosis，further speculation that thrombosis is not the main cause of CRAO. 　　Key words：Central retinal artery occlusion；Risk factors；Coagulation function；Prothrombin time；Activated partial thromboplastin time 　　?网膜中央动脉阻塞（central retinal artery occlusion，CR