解毒消痤汤治疗寻常型痤疮临床效果研究.docVIP

解毒消痤汤治疗寻常型痤疮临床效果研究 　　[摘要] 目的 探究解毒消痤汤治疗寻常型痤疮的临床效果。 方法 整群选取该院中医科门诊182例寻常型痤疮患者作为研究对象，将所有患者随机分为研究组与对照组，对照组患者口服维胺酯胶囊治疗，研究组患者则采取解毒消痤汤治疗，对比两组患者治疗效果及不良反应。 结果 治疗后研究组总有效率98.09%，对照组87.91%，差异有统计学意义（P0.05）；研究组患者出现1例恶心，对照组出现2例恶心，3例口干，2例舌红，2例困乏，总不良反应率对比χ2=7.7532（P=0.0054），差异有统计学意义（P0.05）。 结论 解毒消痤汤治疗寻常型痤疮临床效果良好，可明显改善患者临床症状，促进患者皮肤恢复健康，且不良反应少，安全可行，具有较高的临床应用以及推广价值。 　　[关键词] 解毒消痤汤；寻常型痤疮；总有效率 　　[中图分类号] R59 [文献标识码] A [文章编号] 1674-0742（2015）09（c）-0150-02 　　[Abstract] Objective To explore the clinical effect of Jiedu Xiaocuo soup for treatment of acne vulgaris. Methods 182 outpatients with acne vulgaris in Department of Traditional Chinese Medicine in the hospital were enrolled and divided into study group and control group. The patients in the control group received viaminate capsules orally， while those in the study group were treated with Jiedu Xiaocuo soup. The efficacy and adverse events were compared between the two groups. Results After treatment， there was statistically significant difference in overall effective rate （98.09% vs 87.91%） between the study group and control group， P0.05. The adverse event in the study group included 1 case of nausea， while that in the control group included 2 cases of nausea， 3 cases of dry mouth， 2 cases of red tongue， 2 cases of sleepy， and there was statistically significant difference between the two group in this respect， χ2=7.7532， P=0.00540.05. Conclusion Jiedu Xiaocuo soup can bring remarkable effect for treating acne vulgaris， especially on improving clinical symptoms and promoting skin health with less adverse events and high safety， therefore it is worthy of application and promotion in clinical practice. 　　[Key words] Jiedu Xiaocuo soup； Acne vulgris； Total effective rate 　　寻常型痤疮是一种毛囊皮脂腺结构的慢性炎症皮肤病，中医称之为“粉刺”，该病多见于12～24岁青少年，发病率高达85.0%，而成年人中仍然有3.0%～8.0%患有痤疮[1]。该病病程较长，可能迁延数年，少数患者可自愈，大多数患者都可能留下不同程度的瘢痕与色素沉着。痤疮除了造成患者病损局部不适外，还会一定程度影响患者心理健康。目前，寻找一种安全理想、经济有效的临床治疗方案成为中医皮肤科关注的焦点问题。该院在2013年3月―2015年4月整群选取182例寻常型痤疮患者进行解毒消痤汤治疗效果研究，取得良好结果，现报道如下。 　　1