降眼压治疗对非动脉炎性前部缺血性视神经病变眼部血流动力学影响.docVIP

降眼压治疗对非动脉炎性前部缺血性视神经病变眼部血流动力学影响 　　【摘要】目的探讨分析临床中降眼压治疗对非动脉炎性前部缺血性视神经病变眼部血流动力学的影响。方法90例(110只患眼)非动脉炎性前部缺血性视神经病变患者为研究对象, 将其按照随机数字法分为研究组和对照组, 研究组45例(60只患眼), 对照组45例(50只患眼), 两组均给予常规的治疗, 研究组给予降眼压治疗, 而对照组不给予降眼压治疗, 观察两组眼部血流动力学的变化。结果眼动脉、视网膜中央动脉治疗前研究组和对照组的PI、RI和PSV指标比较差异无统计学意义(P0.05)。治疗后研究组较治疗前的搏动指数(PI)、阴力指数(RI)和收缩期峰血流速度(PSV)指标有明显的改善, 且组间的数据比较差异有统计学意义(P0.05)。结论对于非动脉炎性前部缺血性视神经病变患者患者采取降眼压治疗是可行的, 能够有效的改善患者眼部血流动力状况, 值得临床中应用与推广。 　　【关键词】非动脉炎性；缺血性视神经病变；血流动力学；降眼压；临床疗效 　　 　　Effect of intraocular pressure lowering therapy on ocular hemodynamics of non-arteritic anterior ischemic optic neuropathy QIN Hong, LI Yan-song. Department of Ophtalmology, Qingdao 266071, China 　　【Abstract】Objective To analyze impact of intraocular pressure(IOP) lowering therapy on ocular hemodynamics of non-arteritic anterior ischemic optic neuropathy(AION). Methods Divided, 90 cases(110 affected eyes) of non-arteritic anterior ischemic optic neuropathy into study group(45 patients with 60 affected eyes) and control group(45 patients with 50 affected eyes), both groups were given conventional treatment, study group was given IOP lowering treatment, ocular hemodynamic changes were observed. Results PI, RI and PSV indicators of two groups compared with statistically insignificant difference before ophthalmic artery and central retinal artery treatment(P0.05). PI, RI and PSV indicators of study group significantly improved after treatment, differences were statistically significant(P0.05). Conclusion It is feasible to use IOP lowering therapy on non-arteritic anterior ischemic optic neuropathy, which can effectively improve ocular hemodynamic status of patients, so it is worthy of clinical application and promotion. 　　【Key words】Non-arteritic; Ischemic optic neuropathy; Hemodynamic; Lowering intraocular pressure; Clinical effect 　　非动脉炎性前部缺血性视神经病变在眼科中属于常见疾病, 该病的发生与颈动脉粥样硬化和血流动力学变化以及斑块形成有着密切的联系。其中, 眼压与血压的变化均是影响眼部血流动力学的重要因素［1］。因此, 为了有效的提高该病的治疗效果。本文旨在分析降眼压治疗对非动脉炎性前部缺血性视神经病变眼部血流动力学的影响, 从而为临床中治疗该病提供判断, 具体的报告如下。 　　1资料