饮食与运动干预对肥胖型多囊卵巢综合征不孕症患者代谢状态影响.docVIP

饮食与运动干预对肥胖型多囊卵巢综合征不孕症患者代谢状态影响 　　[摘要] 目的 研究饮食与运动干预对肥胖型多囊卵巢综合征不孕症患者代谢状态的影响。方法 方便选取2012年5月―2017年5月于该院就诊的肥胖型多囊卵巢综合征患者584例，采用随机数字表法将其分为对照组和观察组，各292例。对照组给予常规治疗及护理，观察组在此基础上进行饮食与运动干预。对比两组的干预效果。 结果 干预后，两组体重无明显变化，差异无统计学意义（P0.05）；但观察组患者的腰臀比以及体脂率均显著下降，分别为（0.83±0.02）、（31.17±4.54）%，且明显低于对照组，差异有统计学意义（P0.05）；干预后，观察组空腹血糖、空腹胰岛素、胰岛素抵抗指数和喝75 g糖水后2 h血糖，2 h胰岛素分别为（5.11±0.63）mmol/L、（6.0±4.65）mU/L、（0.30±0.12）、（5.74±0.59）mmol/L、（8.57±3.34）mU/L，均低于对照组，差异有统计学意义（P0.05）。 结论 针对肥胖型多囊卵巢综合征患者进行饮食与运动干预，可有效帮助患者降低体脂含量，降低患者的胰岛素抵抗，提高基础代谢。 　　[关键词] 多囊卵巢综合征；肥胖型；饮食与运动干预；代谢状态 　　[中图分类号] R711 [文献标识码] A [文章编号] 1674-0742（2017）12（b）-0104-04 　　[Abstract] Objective To research the effect of Diet and exercise intervention on the metabolic state of patients with Obesity type polycystic ovary syndrome sterility. Methods 584 cases of patients with obesity type polycystic ovary syndrome sterility diagnosed in our hospital from May 2012 to May 2017 were convenient selected and randomly divided into two groups with 292 cases in each， the control group adopted the routine treatment and nursing， while the observation group adopted the diet and exercise intervention on the basis of the control group， and the intervention effect was compared between the two groups. Results After intervention， the difference in the weight between the two groups was not statistically significant（P0.05）， but the waist-to-hipratio and body fat rate in the observation group obviously decreased， [（0.83±0.02） and（31.17±4.54）%]， which were obviously lower than those in the control group， and the differences were statistically significant（P0.05）， after intervention， the fasting blood glucose， fasting insulin， insulin resistance index and 2 h blood glucose and 2 h insulin after drinking 75 g syrup were respectively （5.11±0.63）mmol/L， （6.0±4.65）mU/L， （0.30±0.12）， （5.74±0.59）mmol/L， （8.57±3.34）mU/L， which were lower than those in the control group， and the differences were statistically significant（P0.05）. Conclusion The diet and exercise interventio