鼻外伤对鼻腔生理功能影响研究.docVIP

鼻外伤对鼻腔生理功能影响研究 　　[摘要] 目的 研究鼻外伤对鼻腔生理功能的影响，以期对鼻外伤的诊治产生新的社会及经济价值。方法 随机选取自2013年1月―2014年6月该院因鼻外伤而在门急诊及住院病人100例，通过对其解剖学形态、病理组织学、嗅觉功能测定、鼻腔通气试验等相关鼻腔生理功能检查，研究其影响生理功能的基本原因。结果 100例患者中，平均年龄（42.52±8.75）岁。鼻内镜观察鼻腔呼吸区和嗅区粘膜形态见100例患者中有72例出现鼻中隔脱位或偏曲。有80例患者出现粘膜撕裂或鼻腔血肿形成。取下鼻甲活检标本，100例患者中有82例出现组织表面纤毛部分断裂，黏膜及黏膜下层出现撕裂，黏膜下见炎症细胞浸润，腺体结构欠规则。鼻外伤患者治疗前嗅觉功能明显较术后恢复6个月患者差。术前患者鼻通气阻力值（8.32±1.21），术后6个月鼻通气阻力值（1.49±0.85），两者间差异有统计学意义（P0.05）。术前患者MTR （6.98±0.98），术后MTR （4.05±0.52），两者间差异有统计学意义（P0.05）。结论 鼻外伤对患者鼻腔生理功能存在一定影响，需给予积极治疗。 　　[关键词] 鼻外伤；生理功能；黏膜撕裂；鼻通气 　　[中图分类号] R765.2 [文献标识码] A [文章编号] 1674-0742（2015）08（b）-0022-02 　　[Abstract] Objective To study on the effects of nasal trauma to physiological function of nasal cavity， in order to generate new social and economic value to the diagnosis and treatment of nasal trauma. Methods 100 cases of outpatients and inpatients， because of nasal trauma accepted by our hospital from January 2013 to June 2014， were collected. The basic reason on the influence of physiological function was studied， through related nasal physiological function tests of its anatomic morphology， histopathology， olfactory function test， nasal ventilation test， etc. Results 100 patients with average age of （42.52 ± 8.75） years old. Endoscopic observation of nasal breathing zone and the olfactory mucosa morphology， of 100 patients， 72 patients had nasal septum dislocation or deviation， 80 cases with mucosal torn or nasal hematoma formation. Turbinate removed and sample biopsy were made， of 100 patients， 82 cases’ tissue surface cilia appeared partially broken， mucosa and submucosa torn， submucosal inflammatory cell infiltration seen， and irregular glandular structures. Olfactory function for Nasal trauma patients before treatment was significantly worse compared with that for patients in postoperative recovery of 6 months. Patients’ preoperative nasal airway resistance value was （8.32±1.21）， and the value of 6 months later was （1.49±0.85）， which means difference between the two was statistic