构建葡萄糖立体化教学案例启迪科研创新思维-地球物理学报.PDF

Univ. Chem. 2018, 33 (4), 11−16 11 •教学研究与改革• doi: 10.3866/PKU.DXHX201710003 构建“葡萄糖”立体化教学案例启迪科研创新思维 * 宦双燕 ，王玉枝 湖南大学化学化工学院，长沙 410082 摘要：构建了“葡萄糖”立体化教学案例，将葡萄糖在生命体系中的代谢平衡、消化吸收、分子转运、糖尿病成因、 血糖检测、无创诊断技术、分子诊疗等领域的研究串联起来，从微观与宏观、疾病与健康、生活应用与科研前沿的 不同角度来展示相关内容。将该案例用于化学与生命相关知识的教学，探索其在本科生科研创新思维训练中的应用。 关键词：立体化教学案例；科研创新思维；葡萄糖 中图分类号：G64；O6 Constructing “Glucose” Three-Dimensional Teaching Case for Inspiring Innovative Thinking * HUAN Shuangyan , WANG Yuzhi College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. Abstract: A three-dimensional teaching case was constructed using “glucose” to connect the knowledge points in life science. In this case, the metabolic balance associated with glucose was firstly introduced, and then the digestion, absorption and molecular transport of glucose were discussed. Furthermore, the cause of diabetes and the detection principles of blood glucose were explained. In addition, the noninvasive diagnostic technique and new frontier of molecular diagnosis were represented. A series of “glucose” related research topics were integrated from macro to micro, from disease to health, from life application to scientific research frontier. This “glucose” three-dimensional teaching case was built and applied in the teaching of chemistry and life related knowledge, and it might be helpful to the undergraduates’ research and innovation thinking training. Key Words: Three-dimensional teaching case; Innovative thinking; Glucose 化学类专业导论是湖南大学化学专业学生必修的一门基础导论课程。通过该课程的教学使学生 能够初步了解化学的魅力和化学研究的广泛性，加深学生对化学专业的理解和热爱，同时对培养学 生科学的思维方法、提高分析和解决问题的能力起到积极的作用，为学生将来深入学习无机化学、 有机化学、分析化学、物理化学等专业课程提供必要的基础。其中“化学与生命”章节的教学中， 主要讲授的是生命活动的化学基础，经典讲授模式是按照构成生命的基本物质，如糖类、蛋白质、 核酸、脂类、维生素、生命元素等顺序依次讲解其组成、结构、分类、生物功能等知识，将生命相 关的化学知识化整为零，依次讲解和展开。该模式有利于学生按照类别去掌握生命相关生物小分