献血者血液中抗―HCVHCV―RNA和ALT检测结果探讨.docVIP

献血者血液中抗―HCVHCV―RNA和ALT检测结果探讨 　　DOI：10.16662/j.cnki.1674-0742.2017.11.050 　　[摘要] 目的 研究在患者血液中存在病毒抗体（抗-HCV）、丙氨酸转氨酶（ALT）、丙肝病毒核糖核酸（HCV-RNA）等的情况。方法 方便选取该院血液检验科自2015年11月―2016年11月期间接收的160例献血者血液样本，采取随机数字表法的形式随机分为两组，即为参照组（n=80）与实验组（n=80），将实行ELISA检测的患者作为参照组，将实行NAT检测的患者作为实验组，分析对比两组患者HCV-RNA、抗-HCV以及ALT?z测结果。结果 实验组献血者合格人数为71例，不合格人数为9例，总合格率为88.75%，参照组合格人数29例，不合格人数51例，总合格率36.25%，组间数据差异有统计学意义（P0.05）。 结论 在检测献血者血液中HCV-RNA、抗-HCV以及ALT时ELISA检测与NAT检测均具备一定效果，但是NAT检测能够有效弥补ELISA检测的风险，需要进一步深入分析血液样本传染病检测措施。 　　[关键词] 献血者血液；抗-HCV；HCV-RNA；ALT；检测结果 　　[中图分类号] R446.6 [文献标识码] A [文章编号] 1674-0742（2017）04（b）-0050-03 　　Study on Test Results of Anti-HCV， HCV-RNA and ALT in Blood of Blood Donors 　　WANG Yan-hua 　　Department of Clinical Laboratory， Chifeng Hospital for Infectious Disease Control， Chifeng， Inner Mongolia， 024000 China 　　[Abstract] Objective To research the anti- HCV， HCV-RNA and ALT in blood in blood donors. Methods 160 cases of blood samples admitted and treated in our hospital from November 2015 to November 2016 were convenient selected and randomly divided into two groups with 80 cases in each， the control group were given the ELISA test， while the experimental group were given the NAT test， and the anti-HCV， HCV-RNA and ALT test results were compared between the two groups. Results There were 71 qualified cases and 9 unqualified cases and the total qualified rate was 88.75% in the experimental group， and in the control group， 29 cases were qualified and 51 cases were unqualified， and the total qualified rate was 36.25%， and the differences between groups were obvious with statistical significance， P0.05. Conclusion Both ELISA test and NAT test in testing the anti-HCV， HCV-RNA and ALT in blood can produce a certain effect， but the NAT test can effectively make up for the test risk of ELISA， and we need to further analyze the test measures of blood samples infectious diseases. 　　[Key words] Blood of donors； Anti-HCV； HCV-RNA； ALT； Test results 　　丙型肝炎可以通过血液以及体液进行传播，大约占据输血传播发生肝炎概率的7