米非司酮和复方米非司酮在药物流产中疗效比较分析.docVIP

米非司酮和复方米非司酮在药物流产中疗效比较分析 　　[[摘要] 目的 对比分析米非司酮与复方米非司酮用于药物流产的疗效。方法 随机选择2013年1月―2015年2月期间在该院行药物流产的100例孕妇作为研究对象，随机分为对照组和观察组，各50例。药物流产：对照组采用单方米非司酮，观察组采用复方米非司酮，比较两组流产结果、孕囊排出时间、流产后出血时间，统计流产后出血量及不良反应情况。 结果 观察组完全流产率（94.0%）显著高于对照组（80.0%），观察组孕妇孕囊排出时间、流产后出血时间（流血量）均显著少于对照组，组间差异有统计学意义（P0.05）。观察组不良反应率为16.0%，显著低于对照组（30.0%），组间差异有统计学意义P0.05。结论 药物流产中应用复方米非司酮流产效果较为理想。 　　[关键词] 复方米非司酮；单方米非司酮；药物流产；双炔失碳酯 　　[中图分类号] R169 [文献标识码] A [文章编号] 1674-0742（2016）09（a）-0132-03 　　[Abstract] Objective Comparison and analysis the curative effect of compound mifepristone and mifepristone used for medical abortion.Methods Random choice during January 2013 ― February 2013 in our hospital 100 cases of pregnant women in line of medical abortion as the research object， were randomly divided into control group and observation group， 50 cases each. Drug abortion： the control group using mifepristone unilaterally， observation group used compound mifepristone， compare the results， two groups of abortion pregnant sac discharge time， bleeding time after abortion， blood loss and adverse reactions after abortion. Results Observation group complete abortion rate （94.0%） is significantly higher than control group （80.0%）， observation group of pregnant women pregnant bursa discharge time， bleeding time after abortion （bleeding amount） are significantly less than the control group， the difference between groups （P 0.05）. Observation group adverse reaction rate was 16.0%， significantly lower than the control group （30.0%）， the difference between group P 0.05. Conclusion Application of compound mifepristone abortion in drug abortion effect is more ideal， amount of bleeding after miscarriage and duration is relatively small， the clinical curative effect is better than that of unilateral mifepristone. 　　[Key words] Compound mifepristone； Unilateral mifepristone； A medical abortion； Double acetylene carbon loss ester 　　米非司酮是常用药物流产常用药物，终止早孕疗效可靠，其配伍米索前列醇用于药物流产效果可靠，临床应用广泛[1]。近年来，复方米非司酮制剂临床应用增多，为进一步明确单方与复方米非司酮药流效果差异性，该研究随机选择