高压电烧伤大鼠血清脂联素、纤维蛋白酶变化及乌司 他丁干预作用-外科学专业论文.docxVIP

万方数据 万方数据 目 录 中文摘要····································································································1 英文摘要····································································································4 英文缩写····································································································8 研究论文 高压电烧伤大鼠血清脂联素、纤维蛋白酶的变化及乌司他 丁干预作用 前言····································································································9 材料与方法······················································································11 结果··································································································14 附图··································································································16 附表··································································································22 讨论··································································································26 结论··································································································31 参考文献··························································································32 综述 烧伤后血细胞流变性及免疫功能变化的研究进························37 致谢··········································································································49 个人简历··································································································50 中 中 文 摘 要 PAGE 10万方数据 PAGE 10 万方数据 高压电烧伤大鼠血清脂联素、纤维蛋白酶变化及乌司他丁干预作 用 摘 要 目的：高压电烧伤不仅对机体造成热力损伤，电流经过身体，电场作 用对机体血管、神经各组织均造成不同程度的损伤。目前，国内外专家学 者对高压电烧伤后毛细血管血流动力学改变的研究已经广泛的开展。研究 表明，电烧伤后血管内皮损伤，局部及全身的炎症反应造成血流动力学异 常改变，以及血栓形成造成微循环出现障碍。电烧伤后导致全身炎症反应 及 血 流 动 力 学 改 变 的 因 素 有 很 多 ， 其 中 血 浆 中 的 脂 联 素 (Adiponectin,ADP)、纤维蛋白酶（Brinase）在调节炎症反应及血流动力学 方面有着重要的作用。脂联素 是脂肪细胞分泌的一种具有多种生物学效 应的蛋白类物质，它以内分泌方式循环于血液中，在机体内参与多种生命 活动的调节。纤维蛋白酶以往是从米曲霉中提取的蛋白酶，能够分解血凝 HYPERLINK /view/174945.htm 块的纤维蛋白和降低 HYPERLINK /view/43423.htm 血浆中 HYPERLINK /view/1756071.htm 纤溶酶抑制物的浓度。电烧伤后对于大鼠血清 纤维蛋白酶的