不同比例珊瑚骨和自体碎骨早期干预拔牙窝的临床研究-口腔临床医学专业论文.docxVIP

万方数据 万方数据 Abstract ABSTRACT Background: Studies have shown that a reduction in ridge dimensions takes place at the first month after tooth extraction. In particular, loss of the bundle bone results in obvious horizontal bone loss and vertical ridge reduction on the facial plate. This process of bone remodeling will aggravate the reduction of soft tissue, creating a clinical challenge for the implant surgeries and a burdened patient with higher esthetic problems. The early-stage interventions on fresh extraction socket may aid in preventing or reducing the physiological resorptive hard tissue and soft tissue processes. Objective: The aim of the study was to clinically, histologically and radiologically evaluate the effects of the fresh extraction socket bone regeneration with mixtures of coralline hydroxyapatite(CHA) and autogenous bone(AB) under different ratios, and the applied value of autogenous bone in sockets site preservation. Material and methods: 60 patients were randomly selected, evenly assigned to four different groups: group A(blood clot), group B(CHA), group C(mixture of 80% CHA and 20% AB) and group D(mixture of 50% CHA and 50% AB). All samples were subjected to clinical examination, Oral plaster casts and panoramic pantomogram at two time points, before tooth extraction and 3~4 months after socket grafting. The sockets were filled with biomaterial according to the groupings following atraumatic extraction and thorough socket debridement. After a 3~4 months follow-up, using a 2mm diameter trephine to obtain a 6~8mm longitudinal bone core. Using a digital caliper to analyze the plaster casts, and the tomography datas were conducted by image analysis software PACS( Carestream，11.0 version), while the histological data were processed by image analysis software ImageJ. Results: Differences were significant revealed between the contrast group and the test groups by oral plaster casts, radiographic and histological analysis(P0.001). IV 摘要 Higher p