二代酪氨酸激酶抑制剂治疗慢性髓性白血病的初步疗效观察-内科学(血液病学)专业论文.docxVIP

目 录 英文缩略词................................................................................................1 中文摘要....................................................................................................2 英文摘要....................................................................................................5 前言............................................................................................................9 对象与方法..............................................................................................10 1. 研究对象.....................................................................................10 2. 方法.............................................................................................11 3. 治疗方案.....................................................................................11 4. 疗效及不良反应评估.................................................................12 5. 观察指标.....................................................................................14 6. 统计分析方法………………………….………………………14 结果..........................................................................................................14 1.患者基本资料...............................................................................14 2.治疗调整情况...............................................................................16 2.1 尼洛替尼治疗调整情况............................................................16 2.2 达沙替尼治疗调整情况............................................................16 3.疗效评估………………………………….…..............................17 3.1 尼洛替尼疗效评估……............................................................17 3.2 达沙替尼疗效评估……............................................................21 4.安全性评价………………...........................................................24 4.1 尼洛替尼安全性评价…............................................................24 4.2 达沙替尼安全性评价…............................................................26 讨论............................................................